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Titolo:
Cutaneous breast angiosarcoma after conserving treatment of breast cancer
Autore:
Hildebrandt, G; Mittag, M; Gutz, U; Kunze, ML; Haustein, UF;
Indirizzi:
Univ Leipzig, Dept Radiotherapy, D-04103 Leipzig, Germany Univ Leipzig Leipzig Germany D-04103 iotherapy, D-04103 Leipzig, Germany Univ Leipzig, Dept Radiooncol, D-04103 Leipzig, Germany Univ Leipzig Leipzig Germany D-04103 adiooncol, D-04103 Leipzig, Germany Univ Leipzig, Dept Dermatol, D-04103 Leipzig, Germany Univ Leipzig Leipzig Germany D-04103 Dermatol, D-04103 Leipzig, Germany Univ Leipzig, Dept Pathol, D-04103 Leipzig, Germany Univ Leipzig LeipzigGermany D-04103 pt Pathol, D-04103 Leipzig, Germany
Titolo Testata:
EUROPEAN JOURNAL OF DERMATOLOGY
fascicolo: 6, volume: 11, anno: 2001,
pagine: 580 - 583
SICI:
1167-1122(200111/12)11:6<580:CBAACT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONSERVATIVE SURGERY; RADIATION-THERAPY; CARCINOMA; RADIOTHERAPY; LYMPHEDEMA;
Keywords:
angiosarcoma; breast cancer; breast conserving therapy; lymphedema; radiotherapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Hildebrandt, G Univ Leipzig, Dept Radiotherapy, Stephanstr 11, D-04103 Leipzig, Germany Univ Leipzig Stephanstr 11 Leipzig Germany D-04103 Germany
Citazione:
G. Hildebrandt et al., "Cutaneous breast angiosarcoma after conserving treatment of breast cancer", EUR J DERM, 11(6), 2001, pp. 580-583

Abstract

Cutaneous angiosarcoma is a rare malignancy that sometimes occurs as a late sequela of breast conservation therapy. We report on a 79-year-old femalewho developed well-differentiated angiosarcoma. in a lymphedematous left breast 5.5 years after surgery and radiotherapy for early invasive ductal breast cancer. The initial appearance was very similar to late radiation dermatitis, and histologically interpreted as scar tissue with atypical vascular lesion. The lesion progressed further, and was clinically suspicious for angiosarcoma. Thus, a second biopsy was taken which confirmed the diagnosis. A complete mastectomy removed all the tumor with clear margins. However, within a period of 16 months she presented four local recurrences which were treated by wide local excision. At present, the patient is free of locally recurrent tumour for 7 months. The few cases of breast angiosarcoma afterbreast conservation therapy reported so far demonstrate that these lesionsare difficult to diagnose due to their rarity and their highly variable and benign appearance, which sometimes may mimic radiation-induced cutaneous changes. Since chronic lymphedema possibly contributes to the development of angiosarcoma, long-term clinical surveillance of these patients is recommended. Biopsies should be taken if new skin lesions occur.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/06/20 alle ore 23:17:05