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Titolo:
Primary cardiac tumours: when is surgery necessary?
Autore:
Stiller, B; Hetzer, R; Meyer, R; Dittrich, S; Pees, C; Alexi-Meskishvili, V; Lange, PE;
Indirizzi:
Deutsch Herzzentrum, Dept Pediat Cardiol, D-13353 Berlin, Germany Deutsch Herzzentrum Berlin Germany D-13353 diol, D-13353 Berlin, Germany Deutsch Herzzentrum, Dept Cardiothorac & Vasc Surg, D-13353 Berlin, Germany Deutsch Herzzentrum Berlin Germany D-13353 Surg, D-13353 Berlin, Germany Deutsch Herzzentrum, Dept Pathol, D-13353 Berlin, Germany Deutsch Herzzentrum Berlin Germany D-13353 thol, D-13353 Berlin, Germany Charite Berlin, Dept Pediat Cardiol, Berlin, Germany Charite Berlin Berlin Germany lin, Dept Pediat Cardiol, Berlin, Germany
Titolo Testata:
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
fascicolo: 5, volume: 20, anno: 2001,
pagine: 1002 - 1006
SICI:
1010-7940(200111)20:5<1002:PCTWIS>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACARDIAC TERATOMA; TUBEROUS SCLEROSIS; TUMORS; BENIGN; HEART; RHABDOMYOMAS; CHILDHOOD; CHILDREN; INFANTS;
Keywords:
cardiac tumour; children; rhabdomyoma; fibroma; teratoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Stiller, B Deutsch Herzzentrum, Dept Pediat Cardiol, Augustenburger Pl 1, D-13353 Berlin, Germany Deutsch Herzzentrum Augustenburger Pl 1 Berlin Germany D-13353
Citazione:
B. Stiller et al., "Primary cardiac tumours: when is surgery necessary?", EUR J CAR-T, 20(5), 2001, pp. 1002-1006

Abstract

Objective: Primary cardiac tumours are rare. The literature predominantly contains series on myxomas in adults and only a few long-term series that involve the very different primary cardiac tumours in early childhood. As foetal ultrasonography has continued to improve, cardiac tumours are increasingly detected early before significant symptoms develop. It is a challenge for paediatric cardiologists and surgeons to ascertain which patients need surgery and which will benefit from conservative follow-up. Methods: A retrospective review of a 10-year period revealed 51 tumours in 26 children (median age: 1 month). Analysis was by presentation, location, associated findings, interventions, histological findings, and clinical course. Results: The most common tumours were rhabdomyomas (29), fibromas (nine), teratomas (two), and haemangiomas (two). The tumour location was the right ventricle in 24 and the left ventricle in 22 patients. The symptoms varied between abnormal heart murmur (20), arrhythmia and conduction abnormalities (ten), obstruction of the outflow tract > 30 mmHg (nine), severe cyanosis (three) andcongestive heart failure (two). Four-teen children with haemodynamic compromises under-went sur 'gery. There was one post-operative death and one heart transplantation after bridging with an assist device. There was no tumour recurrence even when resection was incomplete. Nine of 13 children with rhabdomyomas had spontaneous tumour regression without intervention.Conclusions: Most of the cardiac tumours in children are benign. Spontaneous regression is possible not only in rhabdomyoma. Surgical intervention is only required for children who develop relevant clinical symptoms. Total resection of the tumour is not the only therapeutic aim; more important is the restoration of the best possible heart function. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 01:07:57