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Titolo:
International Council of Emboli Management (ICEM) Study Group results: risk adjusted outcomes in intraaortic filtration
Autore:
Schmitz, C; Blackstone, EH;
Indirizzi:
Klin & Poliklin Herzchirurg, D-53105 Bonn, Germany Klin & Poliklin Herzchirurg Bonn Germany D-53105 , D-53105 Bonn, Germany Cleveland Clin Fdn, Cleveland, OH 44195 USA Cleveland Clin Fdn Cleveland OH USA 44195 in Fdn, Cleveland, OH 44195 USA
Titolo Testata:
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
fascicolo: 5, volume: 20, anno: 2001,
pagine: 986 - 990
SICI:
1010-7940(200111)20:5<986:ICOEM(>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARDIAC-SURGERY; PARTICULATE EMBOLI; BYPASS-SURGERY; STROKE; CAPTURE;
Keywords:
intraaortic filtration; neurologic outcomes; Stroke Risk Index; coronary artery bypass grafting; cardiopulmonary bypass;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Schmitz, C Klin & Poliklin Herzchirurg, Sigmund Freud Str 25, D-53105 Bonn, Germany Klin & Poliklin Herzchirurg Sigmund Freud Str 25 Bonn Germany D-53105
Citazione:
C. Schmitz e E.H. Blackstone, "International Council of Emboli Management (ICEM) Study Group results: risk adjusted outcomes in intraaortic filtration", EUR J CAR-T, 20(5), 2001, pp. 986-990

Abstract

Background: The Multicenter Study of Perioperative Ischemia (McSPI) developed and validated a Stroke Risk Index for estimating the likelihood that patients undergoing isolated coronary artery bypass grafting will experience major perioperative neurologic events. The International Council of Emboli Management (ICEM) Study Group has suggested that use of intraaortic filtration reduces adverse neurologic events. Objective: The objective of the present study was to compare predicted and observed neurologic outcomes in patients receiving intraaortic filtration. Patients and Methods: From February 1999 to August 2000, 962 patients were enrolled consecutively in a prospective, nonvoluntary registry of intraaortic filtration in 15 European centers. Of these, 447 underwent isolated coronary artery bypass grafting, the target population for applying the McSPI Stroke Risk Index. Forty-five had incomplete data, yielding a study group of 402 patients. The Stroke Risk Indexwas calculated for each patient, and the sum across patients yielded an expected number of neurologic events. These were compared to observed events by confidence limits and goodness of fit. Results: Six neurologic events were observed (1.5%; 95% confidence limits 0.6-3.4%), roughly half the 13.7 predicted by the Stroke Risk Index (3.4%; 95% confidence limits 2.0-5.8%) P = 0.03. Conclusions: Adverse neurologic events associated with coronary artery bypass grafting in which intraaortic filtration was used were rare and fewer than expected on the basis of the Stroke Risk Index. Rare occurrence of clinically relevant events precludes their use as primary endpoints for randomized clinical studies; however, the Stroke Risk Index provides a valuable benchmark in the absence of such studies. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 11:51:33