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Titolo:
Genetics and the common cancers
Autore:
Peto, J; Houlston, RS;
Indirizzi:
Inst Canc Res, Epidemiol Sect, Sutton SM2 5NG, Surrey, England Inst Canc Res Sutton Surrey England SM2 5NG tton SM2 5NG, Surrey, England Univ London London Sch Hyg & Trop Med, London WC1E 7HT, England Univ London London Sch Hyg & Trop Med London England WC1E 7HT T, England Inst Canc Res, Sect Canc Genet, Sutton SM2 5NG, Surrey, England Inst Canc Res Sutton Surrey England SM2 5NG tton SM2 5NG, Surrey, England
Titolo Testata:
EUROPEAN JOURNAL OF CANCER
, volume: 37, anno: 2001, supplemento:, 8
pagine: S88 - S96
SICI:
0959-8049(200110)37:<S88:GATCC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
S-TRANSFERASE M1; BREAST-CANCER; BLADDER-CANCER; LUNG-CANCER; SUSCEPTIBILITY GENE; COLORECTAL CANCERS; RISK; LOCUS; MELANOMA; LINKAGE;
Keywords:
cancer genetics; low-penetration genes; linkage analysis; segregation analysis; review;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Peto, J Inst Canc Res, Epidemiol Sect, Sutton SM2 5NG, Surrey, England Inst Canc Res Sutton Surrey England SM2 5NG 5NG, Surrey, England
Citazione:
J. Peto e R.S. Houlston, "Genetics and the common cancers", EUR J CANC, 37, 2001, pp. S88-S96

Abstract

Rare highly penetrant genes cannot account for much of the familial risk for most common cancers, and there is increasing evidence that a high proportion of cancers arise in a susceptible minority who carry low-penetrance genes or gene combinations. The evidence for the existence of such genes and the prospects for identfying them are reviewed. (C) 2001 Published by Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 11:59:14