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Titolo:
Dietary fats in the prevention of coronary heart disease: the need for more clinical trials
Autore:
Barringer, TD;
Indirizzi:
Carolinas Hlth Care Syst, Dept Family Practice, Charlotte, NC 28232 USA Carolinas Hlth Care Syst Charlotte NC USA 28232 , Charlotte, NC 28232 USA
Titolo Testata:
EUROPEAN HEART JOURNAL SUPPLEMENTS
fascicolo: D, volume: 3, anno: 2001,
pagine: D79 - D84
SICI:
1520-765X(200106)3:D<D79:DFITPO>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
FISH CONSUMPTION; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; RISK-FACTORS; FOLLOW-UP; FLAVONOID INTAKE; NUT CONSUMPTION; ARTERY DISEASE; WOMEN; MORTALITY;
Keywords:
n-3 fats; Mediterranean diet; whole dietary pattern;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Barringer, TD Carolinas Hlth Care Syst, Dept Family Practice, CHC-MP Bldg,POB 32861, Charlotte, NC 28232 USA Carolinas Hlth Care Syst CHC-MP Bldg,POB32861 Charlotte NC USA 28232
Citazione:
T.D. Barringer, "Dietary fats in the prevention of coronary heart disease: the need for more clinical trials", EUR H J SUP, 3(D), 2001, pp. D79-D84

Abstract

On the basis of various lines of evidence, including clinical trials, dietappears to have the potential to lessen the risk of CHD events, independent of effects on serum lipid values, at least as great as the most effectivemedical and interventional treatments available today. Given the diversityof these cardioprotective diets, as well as their salutary components, oneof the priorities in research should be to undertake more comparative trials, trials which determine patient acceptability, effects on surrogate markers of risk, and which ultimately impact on morbidity and mortality. The Carolina Diet Heart Trial is a clinical outcome trial comparing two 'proven' cardioprotective diets, the AHA endorsed Step II diet versus an American-Mediterranean diet, and having the amount and type of unsaturated fat as the main dependent variable. This study is a prospective, randomized, multi-centre, secondary prevention trial with the ultimate intention of reducing the incidence of subsequent cardiovascular events through dietary modification in patients who have survived a previous acute coronary syndrome. The study intervention is also designed to give these patients the necessaryknowledge, motivation and practical ability to modify their current diets and maintain long-term adherence to a more cardioprotective diet. The initial pilot phase will assess compliance with the two study diets, as well as assess the impact of each diet on a marker of CHD risk. (C) 2001 The European Society of Cardiology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 10:54:05