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Titolo:
Early coronary angiography improves long-term survival in unstable angina
Autore:
Mathew, V; Farkouh, ME; Gersh, BJ; Rihal, CS; Reeder, GS; Grill, DE; Urban, LH; Kopecky, SL; Chesebro, JH; Holmes, DR;
Indirizzi:
Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 Dis, Rochester, MN 55905 USA Mt Sinai Med Ctr, New York, NY 10029 USA Mt Sinai Med Ctr New York NY USA10029 ai Med Ctr, New York, NY 10029 USA Mayo Clin, Jacksonville, FL 32224 USA Mayo Clin Jacksonville FL USA 32224Mayo Clin, Jacksonville, FL 32224 USA
Titolo Testata:
AMERICAN HEART JOURNAL
fascicolo: 5, volume: 142, anno: 2001,
pagine: 768 - 774
SICI:
0002-8703(200111)142:5<768:ECAILS>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; ARTERY DISEASE; UNITED-STATES; RANDOMIZED TRIAL; CLINICAL-TRIAL; BYPASS SURGERY; GUSTO TRIAL; MANAGEMENT; OUTCOMES; CASS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Mathew, V Mayo Clin & Mayo Fdn, Div Cardiovasc Dis, 200 1st St SW, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn 200 1st St SW Rochester MN USA 55905 05 USA
Citazione:
V. Mathew et al., "Early coronary angiography improves long-term survival in unstable angina", AM HEART J, 142(5), 2001, pp. 768-774

Abstract

Background The role of early coronary angiography in the evaluation of patients with unstable angina has been controversial. This study was designed to determine the effect of early coronary angiography on long-term survivalin patients with unstable angina. Methods We reviewed the Olmsted County Acute Chest Pain Database, a population-based epidemiologic registry that includes all patients residing within Olmsted County who were seen for emergency department evaluation of acutechest pain from 1985 to 1992. Patients with symptoms consistent with myocardial ischemia qualifying as unstable angina were classified as undergoing early (less than or equal to7 days of index presentation) angiography or not. Results A total of 2264 patients with symptoms consistent with unstable angina were identified with a mean duration of follow-up of 6 years; 892 underwent early angiography. Early angiography patients were younger; less likely to have heart failure; more likely to be male, hypercholesterolemic, andsmokers; had prior coronary revascularization; and had a myocardial infarction at the index presentation. After baseline differences were controlled,early angiography was associated with a reduction in all-cause long-term mortality (relative risk 0.63, 95% CI 0.53-0.74). Patients at intermediate or high risk for death or myocardial infarction at presentation were most likely to benefit from early angiography. Conclusion Early angiography in the evaluation of patients with unstable angina was associated with a reduction in all-cause mortality, particularly in intermediate- and high-risk patients, in this retrospective population-based study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 20:55:52