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Titolo:
Lack of correlation between clinical patterns of asthma and airway obstruction
Autore:
Verini, M; Rossi, N; Dalfino, T; Verrotti, A; Di Gioacchino, M; Chiarelli, F;
Indirizzi:
Univ Chieti, Allergol Sect Pediat Clin, Chieti, Italy Univ Chieti ChietiItaly ieti, Allergol Sect Pediat Clin, Chieti, Italy
Titolo Testata:
ALLERGY AND ASTHMA PROCEEDINGS
fascicolo: 5, volume: 22, anno: 2001,
pagine: 297 - 302
SICI:
1088-5412(200109/10)22:5<297:LOCBCP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHILDHOOD ASTHMA; CONSENSUS STATEMENT; PULMONARY-FUNCTION; SEVERITY; CHILDREN; MANAGEMENT; RESPONSIVENESS; SYMPTOMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Verini, M Colle dellAra Hosp, Allergol Sect, Pediat Clin, Via dei Vestini,I-66100 Chieti, Italy Colle dellAra Hosp Via dei Vestini Chieti Italy I-66100 , Italy
Citazione:
M. Verini et al., "Lack of correlation between clinical patterns of asthma and airway obstruction", ALL ASTH P, 22(5), 2001, pp. 297-302

Abstract

dTo evaluate the relationship between the classification of asthma and obstruction of airways, we have studied 100 children suffering from allergic asthma: 65 mates and 35 females, aged 4.2-16.3 years (mean, 7.6 +/- 2.8 years), who were evaluated at least 1 month after the last attack of airway obstruction. We analyzed personal history of all children with special reference to number of attacks of airway obstruction in the lost year, severity, and presence of respiratory symptoms in the last month. The children studiedhave been classified in three groups according to the International Pediatric Respiratory Allergy, Forum (IPRAF) '98 method (Third International Pediatric Consensus Statement on the management of childhood asthma). All children underwent the assessment of their respiratory function by means of analysis of the flow/volume loops with measurement of the obstruction indices (forced expiratory volume in 1 second [FEVI1], peak expiratory flow [PEF], and maximal midexpiratory flow [MMEF]). The efficacy of the aforementioned method has been evaluated by analyzing the number of the subjects who showedindices of airway obstruction not in agreement with. the group assigned. Eighty-five of the children studied were diagnosed with infrequent episodic asthma (IEA), 14 children were diagnosed with frequent episodic asthma (FEA), and 1 child was diagnosed with persistent asthma (PA). Thirty-six of 100children showed obstruction indices not in agreement with the asthma group: in particular, 24 of 85 children with IEA had FEV1 < 80%, 11 children vith FEA had FEV1 > 80%, and 1 child vith PA had FEV1 > 80%. The high percentage of discordance between clinical classification and obstruction index in the subjects vith IEA can be caused by the persistence of abnormalities of the respiratory function without clinical symptoms. The presence of a normal obstruction index in the subjects with FEA can be explained by the pharmacologic therapies. These data suggest the usefulness of a careful evaluation of the respiratory function associated with a clinical assessment to carry out a more appropriate therapy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:30:16