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Titolo:
Molecular epidemiology, biomarkers and cancer prevention
Autore:
Furberg, AH; Ambrosone, CB;
Indirizzi:
Mt Sinai Sch Med, Derald Ruttenberg Canc Ctr, Canc Epidemiol Program, Riyadh 11211, Saudi Arabia Mt Sinai Sch Med Riyadh Saudi Arabia 11211 m, Riyadh 11211, Saudi Arabia
Titolo Testata:
TRENDS IN MOLECULAR MEDICINE
fascicolo: 11, volume: 7, anno: 2001,
pagine: 517 - 521
SICI:
1471-4914(200111)7:11<517:MEBACP>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER; GENETIC POLYMORPHISMS; LUNG-CANCER; CIGARETTE-SMOKING; RISK; SUSCEPTIBILITY; ASSOCIATION; ISOTHIOCYANATES; METAANALYSIS; POPULATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Furberg, AH Mt Sinai Sch Med, Derald Ruttenberg Canc Ctr, Canc Epidemiol Program, 1 Gustave L Levy Pl,Box 1130, Riyadh 11211, Saudi Arabia Mt Sinai Sch Med 1 Gustave L Levy Pl,Box 1130 Riyadh Saudi Arabia 11211
Citazione:
A.H. Furberg e C.B. Ambrosone, "Molecular epidemiology, biomarkers and cancer prevention", TRENDS MO M, 7(11), 2001, pp. 517-521

Abstract

Molecular epidemiological studies within the field of cancer research provide the potential for elucidating the carcinogenic cascade at the molecularlevel. Identification of susceptible subsets of the population, based on polymorphisms in genes involved in carcinogenesis, has the potential to delineate more clearly those factors that might increase cancer risk among some, but not all, individuals. Rapid advances in human genomics are making it possible to develop detailed profiles of susceptible subgroups based upon genetic variants in multiple pathways. Here we discuss examples of recent susceptibility studies involving genes, such as those involved in carcinogen metabolism, DNA repair, cell cycle and immune status, that hold the promiseof increasing our understanding of cancer etiology and possible preventionstrategies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:13:22