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Titolo:
Evaluation of a dipstick test for the rapid diagnosis of imported malaria among patients presenting within the network TropNetEurop
Autore:
Jelinek, T; Grobusch, MP; Harms, G;
Indirizzi:
Univ Munich, Dept Trop Med & Infect Dis, DE-80802 Munich, Germany Univ Munich Munich Germany DE-80802 Infect Dis, DE-80802 Munich, Germany Charite Humboldt Univ, Med Clin Infect Dis, Berlin, Germany Charite Humboldt Univ Berlin Germany d Clin Infect Dis, Berlin, Germany Charite Humboldt Univ, Inst Trop Med, Berlin, Germany Charite Humboldt Univ Berlin Germany iv, Inst Trop Med, Berlin, Germany Charite Humboldt Univ, Fac Med, Berlin, Germany Charite Humboldt Univ Berlin Germany ldt Univ, Fac Med, Berlin, Germany
Titolo Testata:
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES
fascicolo: 10, volume: 33, anno: 2001,
pagine: 752 - 754
SICI:
0036-5548(2001)33:10<752:EOADTF>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMODIUM-FALCIPARUM MALARIA; ANTIGEN-CAPTURE ASSAY; TRAVELERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Jelinek, T Univ Munich, Dept Trop Med & Infect Dis, Leopoldstr 5, DE-80802Munich, Germany Univ Munich Leopoldstr 5 Munich Germany DE-80802 nich, Germany
Citazione:
T. Jelinek et al., "Evaluation of a dipstick test for the rapid diagnosis of imported malaria among patients presenting within the network TropNetEurop", SC J IN DIS, 33(10), 2001, pp. 752-754

Abstract

Lack of experience on the part of involved laboratory personnel frequentlycomplicates swift diagnosis of imported falciparum malaria in non-endemic areas. Diagnostic tools based on the dipstick principle for the detection of plasmodial histidine-rich protein 2 have been marketed for several years and have been extensively evaluated. Recently, a test kit capable of detecting antigen of Plasmodium falciparum and P. vivax has been introduced. In order to evaluate this newly available tool, specimens from 664 patients were screened during the course of a prospective multicentre study within the European Network on Imported Infectious Disease Surveillance (TropNetEurop). Among the screened specimens, samples from 82 patients (12.3%) were positive for falciparum malaria using expert microscopy. A further 17 samples were positive for vivax malaria. The evaluated test kit performed with a sensitivity of 87.8% and a specificity of 99% for detection of falciparum malaria. Respective values for vivax malaria were 76.5% and 100%. Dipstick testshave the potential of improving the speed and accuracy of the diagnosis offalciparum malaria, especially if non-specialized laboratories are involved. However, decreased values of sensitivity and specificity, in comparison with expert microscopy, still impose a clear limit on the usefulness of thecurrently available kits.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/10/20 alle ore 12:48:33