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Titolo:
Impact of the Minimum Pricing Policy and introduction of brand (generic) substitution into the Pharmaceutical Benefits Scheme in Australia
Autore:
McManus, P; Birkett, DJ; Dudley, J; Stevens, A;
Indirizzi:
Dept Hlth & Aged Care, Drug Utilisat Subcomm MDP 83, Canberra, ACT 2601, Australia Dept Hlth & Aged Care Canberra ACT Australia 2601 ra, ACT 2601, Australia Flinders Med Ctr, Dept Clin Pharmacol, Adelaide, SA, Australia Flinders Med Ctr Adelaide SA Australia harmacol, Adelaide, SA, Australia
Titolo Testata:
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
fascicolo: 4, volume: 10, anno: 2001,
pagine: 295 - 300
SICI:
1053-8569(200106/07)10:4<295:IOTMPP>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Keywords:
drug utilization; pharmacoepidemiology; generic substitution; brand premium; patient tracking;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
10
Recensione:
Indirizzi per estratti:
Indirizzo: McManus, P Dept Hlth & Aged Care, Drug Utilisat Subcomm MDP 83, GPO Box 9848, Canberra, ACT 2601, Australia Dept Hlth & Aged Care GPO Box 9848 Canberra ACT Australia 2601
Citazione:
P. McManus et al., "Impact of the Minimum Pricing Policy and introduction of brand (generic) substitution into the Pharmaceutical Benefits Scheme in Australia", PHARMA D S, 10(4), 2001, pp. 295-300

Abstract

Purpose To describe the effects of introducing the Minimum Pricing Policy (MPP) and generic (brand) substitution in 1990 and 1994 respectively on thedispensing of Pharmaceutical Benefits Scheme (PBS) prescriptions both at the aggregate and individual patient level. Methods The relative proportion of prescriptions with a brand premium and those at benchmark was examined 4 years after introduction of the MPP and again 5 years later after generic substitution by pharmacists was permitted. To determine the impact of a price signal at the individual level, case studies involving a patient tracking methodology were conducted on two drugs (fluoxetine and ranitidine) that received a brand premium. Results From a zero base when the MPP was introduced in 1990, there were 5A million prescriptions (17%) dispensed for benchmark products 4 years later in 1994. At this stage generic (brand) substitution by pharmacists was then permitted and the market share of benchmark brands increased to 45% (25.2 million) by 1999. In the patient tracking studies, a significantly lower proportion of patients was still taking the premium brand of fluoxetine 3 months after the introduction of a price signal compared with patients taking paroxetine which did not have a generic competitor. This was also the case for the premium brand of ranitidine when compared to famotidine The size of the price signal also had a marked effect on dispensing behaviour with the drug with the larger premium (fluoxetine) showing a significantly greater switch away from the premium brand to the benchmark product. Conclusions The introduction in 1990 of the Minimum Pricing Policy withoutallowing generic substitution had a relatively small impact on the selection of medicines within the Pharmaceutical Benefits Scheme. However the effect of generic substitution at the pharmacist level, which was introduced inDecember 1994, resulted in a marked increase in the percentage of eligiblePBS items dispensed at benchmark. Case studies showed a larger premium resulted in a greater shift of patients from drugs with a brand premium to thebenchmark alternative. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 09:13:00