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Titolo:
The neuronal naturalist: watching neurons in their native habitat
Autore:
Lichtman, JW; Fraser, SE;
Indirizzi:
CALTECH, Beckman Inst, Biol Imaging Ctr, Pasadena, CA 91125 USA CALTECH Pasadena CA USA 91125 t, Biol Imaging Ctr, Pasadena, CA 91125 USA Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA Washington Univ St Louis MO USA 63110 & Neurobiol, St Louis, MO 63110 USA
Titolo Testata:
NATURE NEUROSCIENCE
, volume: 4, anno: 2001, supplemento:, S
pagine: 1215 - 1220
SICI:
1097-6256(200111)4:<1215:TNNWNI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
FROG NEUROMUSCULAR-JUNCTIONS; SYNAPTIC EXTRACELLULAR-MATRIX; DENDRITIC CALCIUM DYNAMICS; IN-VIVO; NERVE-TERMINALS; LIVING MICE; INVIVO VISUALIZATION; FLUORESCENT-PROBES; PYRAMIDAL NEURONS; MAP FORMATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
58
Recensione:
Indirizzi per estratti:
Indirizzo: Fraser, SE CALTECH, Beckman Inst, Biol Imaging Ctr, Pasadena, CA 91125 USACALTECH Pasadena CA USA 91125 ging Ctr, Pasadena, CA 91125 USA
Citazione:
J.W. Lichtman e S.E. Fraser, "The neuronal naturalist: watching neurons in their native habitat", NAT NEUROSC, 4, 2001, pp. 1215-1220

Abstract

Dynamic processes of neural development, such as migrations of precursor cells, growth of axons and dendrites, and formation and modification of synapses, can be fully analyzed only with techniques that monitor changes over time. Although there has been long-standing motivation for following cellular and synaptic events in vivo (intravital microscopy), until recently few preparations have been studied, and then often only with great effort. Innovations in low-fight and laser-scanning microscopies, coupled with developments of new dyes and of genetically encoded indicators, have increased boththe breadth and depth of in situ imaging approaches. Here we present the motivations and challenges for dynamic imaging methods, offer some illustrative examples and point to future opportunities with emerging technologies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:29:30