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Titolo:
Electrical activity and development of neural circuits
Autore:
Zhang, LI; Poo, MM;
Indirizzi:
Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA Univ Calif Berkeley Berkeley CA USA 94720 ll Biol, Berkeley, CA 94720 USA Univ Calif San Francisco, Keck Ctr Integrat Neurosci, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA
Titolo Testata:
NATURE NEUROSCIENCE
, volume: 4, anno: 2001, supplemento:, S
pagine: 1207 - 1214
SICI:
1097-6256(200111)4:<1207:EAADON>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT BARREL CORTEX; CLASS-I MHC; VISUAL-CORTEX; SYNAPTIC PLASTICITY; RECEPTOR ACTIVATION; NEURONAL-ACTIVITY; HIPPOCAMPAL-NEURONS; ACTION-POTENTIALS; ADENYLYL-CYCLASE; DENDRITIC SPINES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
105
Recensione:
Indirizzi per estratti:
Indirizzo: Poo, MM Univ Calif Berkeley, Dept Mol & Cell Biol, 229 Stanley Hall, Berkeley, CA 94720 USA Univ Calif Berkeley 229 Stanley Hall Berkeley CA USA 94720 720 USA
Citazione:
L.I. Zhang e M.M. Poo, "Electrical activity and development of neural circuits", NAT NEUROSC, 4, 2001, pp. 1207-1214

Abstract

A distinct feature of the nervous system is the intricate network of synaptic connections among neurons of diverse phenotypes. Although initial connections are formed largely through molecular mechanisms that depend on intrinsic developmental programs, spontaneous and experience-cl riven electricalactivities in the developing brain exert critical epigenetic influence on synaptic maturation and refinement of neural circuits. Selective findings discussed here illustrate some of our current understanding of the effects of electrical activity on circuit development and highlight areas that awaitfurther study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:27:46