Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
In vivo monitoring of microvessels in skin flaps: Introduction of a novel technique
Autore:
Langer, S; Biberthaler, P; Harris, AG; Steinau, HU; Messmer, K;
Indirizzi:
Univ Munich, Inst Surg Res, Hosp Grosshadern, Munich, Germany Univ MunichMunich Germany Surg Res, Hosp Grosshadern, Munich, Germany
Titolo Testata:
MICROSURGERY
fascicolo: 7, volume: 21, anno: 2001,
pagine: 317 - 324
SICI:
0738-1085(2001)21:7<317:IVMOMI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
LASER-DOPPLER FLOWMETRY; INTRAVITAL MICROSCOPY; MICROVASCULAR SURGERY; BLOOD-FLOW; TISSUE; MICROCIRCULATION; FLUORESCENCE; PERFUSION; VIABILITY; SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Langer, S Ruhr Univ Bochum, Clin Plast & Hand Surg, Burn Ctr, Bergmannsheil Trauma Ctr, D-44789 Bochum, Germany Ruhr Univ Bochum Bochum Germany D-44789 -44789 Bochum, Germany
Citazione:
S. Langer et al., "In vivo monitoring of microvessels in skin flaps: Introduction of a novel technique", MICROSURG, 21(7), 2001, pp. 317-324

Abstract

Orthogonal polarization spectral (OPS) imaging was validated against intravital fluorescence microscopy (IFM) for microvascular measurements in skin flaps of hairless mice. Examinations were performed 1, 6, and 24 hours after elevation (n = 8) with both OPS imaging and IFM. A fluorescent dye was a prerequisite for IFM measurements but not for OPS imaging. Our findings show that OPS imaging can visualize the skin flap microcirculation independentfrom the application of fluorescent tracers. From these images, quantitative analysis of functional capillary density (FCD) was feasible. As expected, FCD was significantly lower in the distal part of the flap compared with its base (171.8 +/- 34.7 versus 62.0 +/- 25.6, mean +/- SD; 1 hour data). Comparison of OPS imaging and IFM revealed a significant correlation of FCD values (P < 0.001) at all time points. Given the success of this validationstudy on mouse skin flaps, clinical investigations will have to prove thatOPS imaging can also successfully be used to monitor flaps in humans. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 09:01:31