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Titolo:
Decreased food intake with aging
Autore:
Morley, JE;
Indirizzi:
St Louis Univ, Hlth Sci Ctr, Div Geriatr Med, St Louis, MO 63104 USA St Louis Univ St Louis MO USA 63104 v Geriatr Med, St Louis, MO 63104 USA
Titolo Testata:
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
, volume: 56, anno: 2001,
pagine: 81 - 88
SICI:
1079-5006(200110)56:2<81:DFIWA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
NITRIC-OXIDE SYNTHASE; AGE-RELATED-CHANGES; CORTICOTROPIN-RELEASING-FACTOR; GLUCAGON-LIKE PEPTIDE-1; LEPTIN GENE-EXPRESSION; NUTRITIONAL-STATUS; ADIPOSE-TISSUE; SERUM LEPTIN; BODY-WEIGHT; OLDER MEN;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
116
Recensione:
Indirizzi per estratti:
Indirizzo: Morley, JE St Louis Univ, Hlth Sci Ctr, Div Geriatr Med, 1402 S Grand Blvd,Room M238,St Louis, MO 63104 USA St Louis Univ 1402 S Grand Blvd,Room M238St Louis MO USA 63104
Citazione:
J.E. Morley, "Decreased food intake with aging", J GERONT A, 56, 2001, pp. 81-88

Abstract

There is a physiological decline in food intake with aging. The reasons for the decline in food intake are multifactorial and involve both peripheraland central mechanisms. Altered hedonic qualities of food occur due to alterations in taste and, more particularly, smell with aging. A decline in adaptive relaxation of the fundus of the stomach and an increased rate of antral filling appear to play a role in the early satiation seen in many olderpersons. Cholecystokinin levels are increased with aging and older personsare more sensitive to the satiating effects of this gut hormone. The decline in testosterone levels in older males leads to increased leptin levels and this may explain the greater decline in food intake with aging in the male. Within the hypothalamus, decreased activity of both the dynorphin (kappa opioid) and neuropeptide Y systems occurs in aging rodents. Cytokines arepotent anorectic agents. Many older persons have mild inflammatory disorders that lead to anorexia. Exercise may increase food intake in older persons.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 15:52:08