Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Serological distinction of bovine Salmonella carriers from vaccinated and acutely infected cows
Autore:
House, JK; Smith, BP; Kamiya, D;
Indirizzi:
Univ Calif Davis, Sch Vet Med, Dept Med & Epidemiol, Davis, CA 95616 USA Univ Calif Davis Davis CA USA 95616 Med & Epidemiol, Davis, CA 95616 USA
Titolo Testata:
JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION
fascicolo: 6, volume: 13, anno: 2001,
pagine: 483 - 488
SICI:
1040-6387(200111)13:6<483:SDOBSC>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
LINKED-IMMUNOSORBENT-ASSAY; DAIRY HERDS; CALIFORNIA DAIRIES; DUBLIN INFECTION; MAMMARY-GLAND; MILK SAMPLES; TYPHIMURIUM; ANTIGEN; ELISA; LIPOPOLYSACCHARIDE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: House, JK Univ Calif Davis, Sch Vet Med, Dept Med & Epidemiol, Davis, CA 95616 USA Univ Calif Davis Davis CA USA 95616 demiol, Davis, CA 95616 USA
Citazione:
J.K. House et al., "Serological distinction of bovine Salmonella carriers from vaccinated and acutely infected cows", J VET D INV, 13(6), 2001, pp. 483-488

Abstract

Identification of Salmonella carriers using lipopolysaccharide (LPS) ELISAserology in a Salmonella-infected herd requires distinction of chronicallyinfected cattle from convalescent and vaccinated cows. Cows responding to Salmonella infection and vaccination produce titers to Salmonella LPS that overlap with the lower titers of some Salmonella carriers. The objective ofthis study was to determine if the LPS antigen specificity of the bovine humoral immune response to Salmonella LPS antigens differs following vaccination and acute and chronic Salmonella infection. The study focused on the nondiscriminatory area of Salmonella ELISA serology, specifically, peak-titered sera from Salmonella bacterin-vaccinated and experimentally infected cows and low-titered sera from Salmonella carriers. The LPS serogroup specificity of the IgG, and IgG, response following acute and chronic Salmonella serotype Dublin infection and Salmonella bacterin vaccination was evaluated using 5 Salmonella serogroup (B, D, E1, C3, and C1) LPS ELISA assays. IgG(1) titers of carriers, vaccinated, and acutely infected cows were predominantly O antigen specific. Similarly, the IgG(2) titers of acutely infected cows were also O antigen specific. In contrast, Salmonella carriers produced an IgG(2) response to each of the heterologous LPS antigens (B, E1, C3, andC1) examined. The results of this study indicate that the bovine IgG(2) isotype response to Salmonella LPS is serogroup specific. Conversely, production of IgG(2) antibodies to core Salmonella LPS antigens shared across Salmonella serogroups is a feature. of chronic Salmonella infections.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 13:09:13