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Titolo:
Psychiatric syndromes in cerebellar degeneration
Autore:
Leroi, I; OHearn, E; Margolis, RL;
Indirizzi:
Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Neuropsychiat & Memory Serv, Baltimore, MD 21287 USA Johns Hopkins Univ Baltimore MD USA 21287 y Serv, Baltimore, MD 21287 USA Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21287 USA Johns Hopkins Univ Baltimore MD USA 21287 Neurol, Baltimore, MD 21287 USA Johns Hopkins Univ, Sch Med, Dept Neurosci, Baltimore, MD 21287 USA Johns Hopkins Univ Baltimore MD USA 21287 urosci, Baltimore, MD 21287 USA Johns Hopkins Univ, Sch Med, Program Cellular & Mol Med, Baltimore, MD 21287 USA Johns Hopkins Univ Baltimore MD USA 21287 ol Med, Baltimore, MD 21287 USA
Titolo Testata:
INTERNATIONAL REVIEW OF PSYCHIATRY
fascicolo: 4, volume: 13, anno: 2001,
pagine: 323 - 329
SICI:
0954-0261(200111)13:4<323:PSICD>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUNTINGTONS-DISEASE; BASAL GANGLIA; NEUROPSYCHIATRIC ASPECTS; SPINOCEREBELLAR ATAXIA; SCHIZOPHRENIC-PATIENTS; COGNITIVE DYSMETRIA; ONSET SCHIZOPHRENIA; PARKINSONS-DISEASE; VOLUMETRIC MRI; RHESUS-MONKEY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: Leroi, I Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Neuropsychiat & Memory Serv, Osler 320,600 N Wolfe St, Baltimore, MD 21287 USA JohnsHopkins Univ Osler 320,600 N Wolfe St Baltimore MD USA 21287
Citazione:
I. Leroi et al., "Psychiatric syndromes in cerebellar degeneration", INT R PSYC, 13(4), 2001, pp. 323-329

Abstract

The role of the cerebellum in both normal and abnormal processes has undergone substantial reassessment over the past several years. Although the cerebellum's role has traditionally been considered the coordination of voluntary movements, increasing evidence now supports its role in the modulation of cognitive and emotional processing. We review both earlier anecdotal clinical data and newer systematic studies that detected psychiatric changes in patients with cerebellar degeneration (CD); these findings are consistentwith observations in other neurodegenerative diseases. Our own data revealhigh rates of mood disorders, personality change, psychosis, and cognitionin patients with degenerative diseases affecting the cerebellum. These findings have important clinical implications in the management of these patients. In addition, the demonstration that psychiatric disorders may be the consequence of degenerative diseases affecting the cerebellum provides an insight into the neuroanatomical basis for psychopathology, and provides further validation of the general concept that many psychiatric syndromes are rooted in the brain.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/11/19 alle ore 03:45:00