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Titolo:
Fibrinogen, lipoprotein (a) and lipids in patients with erectile dysfunction - A preliminary study
Autore:
Sullivan, ME; Miller, MAW; Bell, CRW; Jagroop, IA; Thompson, CS; Khan, MA; Morgan, RJ; Mikhailidis, DP;
Indirizzi:
Royal Free Hosp, Royal Free & Univ Coll Med Sch, Dept Mol Pathol & Clin Biochem, London NW3 2QG, England Royal Free Hosp London England NW3 2QG Biochem, London NW3 2QG, England
Titolo Testata:
INTERNATIONAL ANGIOLOGY
fascicolo: 3, volume: 20, anno: 2001,
pagine: 195 - 199
SICI:
0392-9590(200109)20:3<195:FL(ALI>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENDOTHELIUM-DEPENDENT RELAXATION; RABBIT CORPUS CAVERNOSUM; LOW-DENSITY LIPOPROTEINS; CARDIOVASCULAR-DISEASE; CIGARETTE-SMOKING; RISK-FACTORS; SMOOTH-MUSCLE; BLOOD RHEOLOGY; IMPOTENT MEN; NITRIC-OXIDE;
Keywords:
impotence; risk factors; cardiovascular diseases; fibrinogen; lipoprotein (a);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
55
Recensione:
Indirizzi per estratti:
Indirizzo: Mikhailidis, DP Royal Free Hosp, Royal Free & Univ Coll Med Sch, Dept Mol Pathol & Clin Biochem, London NW3 2QG, England Royal Free Hosp London England NW3 2QG NW3 2QG, England
Citazione:
M.E. Sullivan et al., "Fibrinogen, lipoprotein (a) and lipids in patients with erectile dysfunction - A preliminary study", INT ANGIOL, 20(3), 2001, pp. 195-199

Abstract

Background. Erectile dysfunction is associated with cardiovascular risk factors (e.g. hypertension, smoking, dyslipidemia and diabetes) and is more common in patients with cardiovascular disease. We therefore assessed the prevalence of two predictors of vascular events, fibrinogen and lipoprotein-a, in patients with and without erectile dysfunction. Methods. Men with erectile dysfunction (48 non-smokers 48 smokers), aged 45-70 years, were compared with controls (21 non-smokers, 21 smokers) with normal erectile function and no known pathology. Results. Serum total cholesterol was significantly higher in non-smokers with erectile dysfunction compared to both control non-smokers and erectile dysfunction smokers. Men with erectile dysfunction who smoked had a significantly higher plasma fibrinogen level than control smokers. Similarly, men with erectile dysfunction, who did not smoke had higher levels of plasma fibrinogen compared to both smokers and non-smokers without erectile dysfunction. No significant difference in serum lipoprotein-a values was found. Conclusions. These findings support the concept that cardiovascular risk factors are predictors of erectile dysfunction and that this may be another manifestation of vascular disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 06:32:25