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Titolo:
New approaches to the treatment of calcium and phosphorus abnormalities inpatients on hemodialysis
Autore:
Uhlig, K; Sarnak, MJ; Singh, AK;
Indirizzi:
Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Renal, Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 ns Hosp, Div Renal, Boston, MA 02115 USA Tufts Univ, Sch Med, New England Med Ctr, Div Nephrol, Boston, MA 02111 USA Tufts Univ Boston MA USA 02111 Med Ctr, Div Nephrol, Boston, MA 02111 USA
Titolo Testata:
CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
fascicolo: 6, volume: 10, anno: 2001,
pagine: 793 - 798
SICI:
1062-4821(200111)10:6<793:NATTTO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC DIALYSIS PATIENTS; BEAM COMPUTED-TOMOGRAPHY; X PHOSPHATE PRODUCT; STAGE RENAL-DISEASE; PARATHYROID-HORMONE; SECONDARY HYPERPARATHYROIDISM; SEVELAMER HYDROCHLORIDE; VALVE CALCIFICATION; VITAMIN-D; ASSOCIATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Singh, AK Harvard Univ, Sch Med, Brigham & Womens Hosp, Div Renal, 75 Francis St, Boston, MA 02115 USA Harvard Univ 75 Francis St Boston MA USA 02115ton, MA 02115 USA
Citazione:
K. Uhlig et al., "New approaches to the treatment of calcium and phosphorus abnormalities inpatients on hemodialysis", CURR OP NEP, 10(6), 2001, pp. 793-798

Abstract

Disturbances in calcium and phosphorus are common in patients who are on chronic hemodialysis. Current therapy consists mainly of administration of calcium-containing phosphate binders and calcitriol. However, the use of these therapies has been limited by both iatrogenic hypercalcemia and hyperphosphatemia. Indeed, hyperphosphatemia and elevations in the calcium x phosphorus product have recently been linked to increased mortality and a high burden of cardiac calcifications on electron-beam computed tomography. Novel therapeutic agents such as sevelamer and vitamin D analogs have thus been developed with the goal of decreasing oral calcium loading and hypercalcemia. We provide an algorithm for the management of calcium and phosphorus abnormalities, based on newer recommendations for tighter calcium and phosphorus control with a lower target for the calcium x phosphorus product. Curr Opin Nephrol Hypertens 10:793-798. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:25:12