Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Focus on ziprasidone
Autore:
Green, B;
Indirizzi:
Univ Liverpool, Royal Liverpool Hosp, Dept Psychiat, Liverpool L69 3BX, Merseyside, England Univ Liverpool Liverpool Merseyside England L69 3BX , Merseyside, England Halton Hosp, Liverpool, Merseyside, England Halton Hosp Liverpool Merseyside England Liverpool, Merseyside, England
Titolo Testata:
CURRENT MEDICAL RESEARCH AND OPINION
fascicolo: 2, volume: 17, anno: 2001,
pagine: 146 - 150
SICI:
0300-7995(2001)17:2<146:FOZ>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLACEBO-CONTROLLED TRIAL; SCHIZOAFFECTIVE DISORDER; ACUTE EXACERBATION; WEIGHT-GAIN; SCHIZOPHRENIA; MG/DAY;
Keywords:
schizophrenia; ziprasidone; antipsychotics; neuroleptics; atypical; pharmacology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Green, B Univ Liverpool, Royal Liverpool Hosp, Dept Psychiat, Liverpool L69 3BX, Merseyside, England Univ Liverpool Liverpool Merseyside England L693BX ide, England
Citazione:
B. Green, "Focus on ziprasidone", CURR MED R, 17(2), 2001, pp. 146-150

Abstract

Ziprasidone is a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. The initial evidence suggests an effective dosage range of 80-160 mg/day. Clinical trials suggest that the drug is an effective antipsychotic in schizophrenia and schizoaffective disorder with a beneficial effect on negative symptoms and symptoms of depression. The main adverse effects appear to be somnolence (14%) and nausea (10%). Ziprasidone has relatively fewer side-effects and yet has at least equivalent efficacy for florid 'positive' symptoms compared with conventional antipsychotics. The additional serotonergic actions deliver further efficacy against 'negative' and affective symptoms of schizophrenia. Reduced effects on cognitive abilities compared to conventional antipsychotics make ziprasidone more attractive still. Barring any unforeseen complications, it appears to a most valuable addition to the antipsychotic agents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:11:22