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Titolo:
Osmotic conditions in rheologic properties of erytrocites
Autore:
Pendas, J; Vila, AO; Rodriguez-Flores, C; Moreiras, T; Figueruelo, J; Molina, F;
Indirizzi:
Univ Valencia, Dept Quim Fis, Unidad Invest Coloides, Burjassot 46100, Valencia, Spain Univ Valencia Burjassot Valencia Spain 46100 assot 46100, Valencia, Spain CNIC, Lab Criobiol & Liofilizac, Havana, Cuba CNIC Havana CubaCNIC, Lab Criobiol & Liofilizac, Havana, Cuba
Titolo Testata:
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
fascicolo: 1-3, volume: 195, anno: 2001,
pagine: 259 - 262
SICI:
0927-7757(200112)195:1-3<259:OCIRPO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIPOSOMES;
Keywords:
electrophoretic mobility; red blood cells; liposomes; dextrose; encapsulation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Molina, F Fac Pharm Montpellier, CNRS UMR 9921, Ave Charles Flahault, F-34000 Montpellier, France Fac Pharm Montpellier Ave Charles Flahault Montpellier France F-34000
Citazione:
J. Pendas et al., "Osmotic conditions in rheologic properties of erytrocites", COLL SURF A, 195(1-3), 2001, pp. 259-262

Abstract

The decreasing viability and in vivo survival of red blood cells, RBCs, observed in blood bank-storage are due to alterations in their rheologic. properties and metabolic status. However, there is a lack of electrokinetic experiments with erythrocytes by the screening produced by the high concentration of buffer required to keep the isoosmotic conditions. Electrokinetic measurements in a wide range of sodium chloride and tetrasodium pyrophosphate are undertaken on liposomes as cell models, and in order to get an aqueous media suitable for maintaining osmotic conditions and allowing electrophoretic. mobility measurements as well, advantage has been taken of dextrose properties. Measured electrokinetic values are practically constant in a wide concentration range of dextrose. With this in mind, the optimal dextroseconcentration for RBCs was determined through the Drabkin's method and itsvalue was inside the above suitable dextrose range. Electrokinetic measurements of RBCs were then undertaken in this medium. (C) 2001 Published by Elsevier Science B.V.

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Documento generato il 04/04/20 alle ore 11:14:27