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Titolo:
The effects of therapeutic electric stimulation on acute muscle atrophy inrats after spinal cord injury
Autore:
Misawa, A; Shimada, Y; Matsunaga, T; Sato, K;
Indirizzi:
Akita Univ, Sch Med, Dept Orthoped Surg, Akita 0108543, Japan Akita Univ Akita Japan 0108543 Dept Orthoped Surg, Akita 0108543, Japan
Titolo Testata:
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
fascicolo: 11, volume: 82, anno: 2001,
pagine: 1596 - 1603
SICI:
0003-9993(200111)82:11<1596:TEOTES>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN SKELETAL-MUSCLE; FIBER-TYPE; HINDLIMB; IMMOBILIZATION; FATIGUE; SOLEUS; SLOW;
Keywords:
electric stimulation; muscular atrophy; rats, Wistar; rehabilitation; spinal cord injuries;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Misawa, A Akita Univ, Sch Med, Dept Orthoped Surg, 1-1-1 Hondo, Akita 0108543, Japan Akita Univ 1-1-1 Hondo Akita Japan 0108543 Akita 0108543, Japan
Citazione:
A. Misawa et al., "The effects of therapeutic electric stimulation on acute muscle atrophy inrats after spinal cord injury", ARCH PHYS M, 82(11), 2001, pp. 1596-1603

Abstract

Objective: To evaluate the effects of electric stimulation in preventing acute muscle atrophy after spinal cord transection in rats. Design: A randomized experimental design. Setting: Animal facilities for experimental medicine. Animals: Fifty-six adult male Wistar rats assigned to control, low-frequency, and high-frequency groups. Interventions: The rats were implanted with a percutaneous intramuscular electrode in the vicinity of the peroneal nerve; then the spinal cord was transected in a T9 level. The stimulation frequency was low (20Hz) or high (100Hz). The stimulation cycle was 4 seconds of stimulation every 8 seconds. Main Outcome Measurements: The lesser fiber diameters from type 1, 2A, and2B muscle fibers were measured. In another assessment. maximal contractionforce was measured. The muscle force produced at 20 and 100Hz was expressed as increasing values in tetanic force,Results: Comparison between nonstimulated and stimulated tibialis anteriormuscles found that atrophy of type I fibers (p < .01) and type 2B fibers (p < .05) at both stimulated levels and of type 2A fibers at 100-Hz level (p< .05) was prevented by therapeutic electric stimulation (TES). There weresignificant differences in the size of muscle fiber diameter between nonstimulated and stimulated muscles at 100Hz in type 2A and. markedly, in type 2B. The increasing value of muscle force was significantly greater at 100Hzthan at 20Hz (p < .05). No significant histologic differences were observed between high- and low-frequency stimulated fibers of any of the 3 muscle types. Conclusions: Acute atrophy of muscle fibers was more effectively preventedby high-frequency stimulation (100Hz) than by no stimulation or low-frequency stimulation (20Hz). The increasing value of muscle force was significantly greater at high-frequency than low-frequency stimulation, suggesting that the clinical application of high-frequency stimulation in acute spinal cord injury should be studied. (C) 2001 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:19:21