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Titolo:
Acute coronary syndromes - The diagnostic role of troponins
Autore:
Hamm, CW;
Indirizzi:
Kerckhoff Heart Ctr, D-61231 Bad Nauheim, Germany Kerckhoff Heart Ctr BadNauheim Germany D-61231 231 Bad Nauheim, Germany
Titolo Testata:
THROMBOSIS RESEARCH
, volume: 103, anno: 2001, supplemento:, 1
pagine: S63 - S69
SICI:
0049-3848(20010930)103:<S63:ACS-TD>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; ST-SEGMENT ELEVATION; UNSTABLE ANGINA; ARTERY DISEASE; RISK STRATIFICATION; PROGNOSTIC VALUE; ANALYTICAL PERFORMANCE; BEDSIDE ASSAY; TASK-FORCE; IMMUNOASSAY;
Keywords:
unstable angina; acute coronary syndrome; troponins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Hamm, CW Kerckhoff Heart Ctr, Benekestr 2-8, D-61231 Bad Nauheim, Germany Kerckhoff Heart Ctr Benekestr 2-8 Bad Nauheim Germany D-61231 ny
Citazione:
C.W. Hamm, "Acute coronary syndromes - The diagnostic role of troponins", THROMB RES, 103, 2001, pp. S63-S69

Abstract

Acute coronary syndromes (ACSs) represent the acute life-threatening phases of coronary heart disease. Clinical symptoms, EKG, and CK-MB measurementsare frequently insufficient to evaluate patients without persisting ST elevations. Serial determinations of troponin T or troponin I after arrival inhospital disclose minor myocardial injury in patients presenting as unstable angina. This finding allows the currently best risk stratification and may contribute to cost-effectiveness. Without elevated troponins the risk for death or myocardial infarction during 30 days follow-up is not more than 1%. The lack of elevated troponins does not implicate that these patients do not have coronary artery disease. Patients with positive evidence of troponins represent a high-risk group who should be hospitalized and further evaluated, because the risk for myocardial infarction and death in 30 days isapproximately 20%. Current studies indicate that early revascularization under glycoprotein IIb/IIIa antagonists represent the optimal treatment. (C)2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:16:39