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Titolo:
Histologic evaluation of fetal brains following maternal pneumoperitoneum
Autore:
Garcia-Oria, M; Ali, A; Reynolds, JD; Clary, E; Gandsas, A; Cummings, T; McMahon, RL; Bruch, S; Fina, M; Ko, A; Eubanks, S;
Indirizzi:
Duke Univ, Med Ctr, Dept Surg, Endosurg Res Lab, Durham, NC 27710 USA DukeUniv Durham NC USA 27710 urg, Endosurg Res Lab, Durham, NC 27710 USA Duke Univ, Med Ctr, Dept Anesthesiol, Endosurg Res Lab, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 iol, Endosurg Res Lab, Durham, NC 27710 USA Duke Univ, Med Ctr, Dept Pathol, Endosurg Res Lab, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 hol, Endosurg Res Lab, Durham, NC 27710 USA
Titolo Testata:
SURGICAL ENDOSCOPY-ULTRASOUND AND INTERVENTIONAL TECHNIQUES
fascicolo: 11, volume: 15, anno: 2001,
pagine: 1294 - 1298
SICI:
0930-2794(200111)15:11<1294:HEOFBF>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARBON-DIOXIDE PNEUMOPERITONEUM; LAPAROSCOPIC SURGERY; CO2 PNEUMOPERITONEUM; PREGNANT EWE; MODEL; INSUFFLATION; LAPAROTOMY; PRESSURE; GROWTH;
Keywords:
pneumoperitoneum; pregnancy; insufflation; laparoscopy; guinea pig; fetus;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Eubanks, S Duke Univ, Med Ctr, Dept Surg, Endosurg Res Lab, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 rg Res Lab, Durham, NC 27710 USA
Citazione:
M. Garcia-Oria et al., "Histologic evaluation of fetal brains following maternal pneumoperitoneum", SURG ENDOSC, 15(11), 2001, pp. 1294-1298

Abstract

Background: The purpose of this study was to determine if maternal pneumoperitoneum with carbon dioxide (CO2) produces evidence of central nervous system (CNS) injury in preterm fetal guinea pigs. Methods: Thirty pregnant guinea pigs at gestational day (GD) 45 were assigned at random to one of three treatment groups: anesthesia only, CO2 pneumoperitoneum (5 mmHg), or laparotomy. Dams were killed 3 or 5 days postprocedure and fetal brains (83 total) harvested and fixed for subsequent histopathologic evaluation. For comparative purposes, histologic features of fetal guinea pig brain injury were defined from examination of fetal brains harvested from an additional dam that underwent laparotomy with 20 min of uterine arterial occlusion. Results: Carbon dioxide pneumoperitoneum did not increase maternal/fetal morbidity. No evidence of brain injury was found in fetuses from any of the treatment groups. Conclusion: Carbon dioxide pneumoperitoneum at 5 mmHg for 40 min in the pregnant guinea pig does not produce evidence of fetal brain injury.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 16:20:15