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Titolo:
Inhibitory effect on immunoglobulin E production in vivo and in vitro by Siegesbeckia glabrescens
Autore:
Kim, HM; Lee, JH; Won, JH; Park, EJ; Chae, HJ; Kim, HR; Kim, CH; Baek, SH;
Indirizzi:
Wonkwang Univ, Coll Pharm, Dept Oriental Pharm, Ctr Oriental Med Sci, Kyung Ju City 780714, Kyungpook, South Korea Wonkwang Univ Kyung Ju City Kyungpook South Korea 780714 ook, South Korea Wonkwang Univ, Coll Oriental Med, Kyung Ju City 780714, Kyungpook, South Korea Wonkwang Univ Kyung Ju City Kyungpook South Korea 780714 ook, South Korea Wonkwang Univ, Sch Dent, Dept Dent Pharmacol, Kyung Ju City 780714, Kyungpook, South Korea Wonkwang Univ Kyung Ju City Kyungpook South Korea 780714 ook, South Korea DongGuk Univ, Coll Oriental Med, Dept Biochem & Mol Biol, Kyung Ju City 780714, Kyungpook, South Korea DongGuk Univ Kyung Ju City Kyungpook South Korea 780714 pook, South Korea Wonkwang Univ, Profess Grad Sch Oriental Med, Dept Nat Prod, Iksan 570749,Chonbuk, South Korea Wonkwang Univ Iksan Chonbuk South Korea 570749 70749,Chonbuk, South Korea
Titolo Testata:
PHYTOTHERAPY RESEARCH
fascicolo: 7, volume: 15, anno: 2001,
pagine: 572 - 576
SICI:
0951-418X(200111)15:7<572:IEOIEP>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
B-CELL DIFFERENTIATION; IGE SYNTHESIS; MAST-CELLS; T-CELLS; INTERLEUKIN-4; INFECTION; IGG1;
Keywords:
Siegesbeckia glabrescens; compositae; IgE; immunization; U266 human IgE-bearing B cells;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, HM Wonkwang Univ, Coll Pharm, Dept Oriental Pharm, Ctr Oriental Med Sci, Sukjang Dong 707, Kyung Ju City 780714, Kyungpook, South Korea WonkwangUniv Sukjang Dong 707 Kyung Ju City Kyungpook South Korea 780714
Citazione:
H.M. Kim et al., "Inhibitory effect on immunoglobulin E production in vivo and in vitro by Siegesbeckia glabrescens", PHYTOTHER R, 15(7), 2001, pp. 572-576

Abstract

Elevated levels of immunoglobulin (Ig)E are associated with immediate-typeallergic reactions. The effect of an aqueous extract of Siegesbeckia glabrescens (Compositae) whole plants (SGWP) on in vivo and in vitro IgE production was studied in mice. SGWP dose-dependently inhibited the active systemic anaphylaxis and serum IgE production induced by immunization with ovalbumin and Bordetella pertussis toxin absorbed to aluminium hydroxide gel. SGWPdose-dependently inhibited IL-4-dependent IgE production by lipopolysaccharide-stimulated murine whole spleen cells. In the case of U266 human IgE-bearing B cells, SGWP also showed an inhibitory effect on IgE production. These results suggest that SGWP has an anti-allergic activity by inhibiting IgE production from B cells. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:09:00