Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Presence of cystic fibrosis-related diabetes mellitus is tightly linked topoor lung function in patients with cystic fibrosis: Data from the European Epidemiologic Registry of Cystic Fibrosis
Autore:
Koch, C; Rainisio, M; Madessani, U; Harms, HK; Hodson, ME; Mastella, G; McKenzie, SG; Navarro, J; Strandvik, B;
Indirizzi:
Univ Gothenburg, Queen Silvia Childrens Hosp, Dept Pediat, Gothenburg, Sweden Univ Gothenburg Gothenburg Sweden Hosp, Dept Pediat, Gothenburg, Sweden Hop Robert Debre, Dept Gastroenterol, F-75019 Paris, France Hop Robert Debre Paris France F-75019 stroenterol, F-75019 Paris, France F Hoffmann La Roche & Co Ltd, Div Pharmaceut, CH-4002 Basel, Switzerland FHoffmann La Roche & Co Ltd Basel Switzerland CH-4002 asel, Switzerland Cyst Fibrosis Ctr, Dept Pulm & Digest Dis & Dev Age, Verona, Italy Cyst Fibrosis Ctr Verona Italy lm & Digest Dis & Dev Age, Verona, Italy Royal Brompton Hosp, Cyst Fibrosis Dept, London SW3 6LY, England Royal Brompton Hosp London England SW3 6LY Dept, London SW3 6LY, England Univ Munich, Childrens Hosp, D-8000 Munich, Germany Univ Munich Munich Germany D-8000 Childrens Hosp, D-8000 Munich, Germany SFR Ltd, Stat Res, Basel, Switzerland SFR Ltd Basel SwitzerlandSFR Ltd, Stat Res, Basel, Switzerland Univ Copenhagen Hosp, Rigshosp, Dept Pediat, DK-2100 Copenhagen, Denmark Univ Copenhagen Hosp Copenhagen Denmark DK-2100 2100 Copenhagen, Denmark
Titolo Testata:
PEDIATRIC PULMONOLOGY
fascicolo: 5, volume: 32, anno: 2001,
pagine: 343 - 350
SICI:
8755-6863(200111)32:5<343:POCFDM>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
PULMONARY-FUNCTION; GROWTH; CHILDREN; SURVIVAL; PATTERNS;
Keywords:
cystic fibrosis; diabetes mellitus; pulmonary function; registry;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Koch, C Rigshosp, Dept Pediat, Juliane Marie Ctr, Blegdamsvej 9, DK-2100 Copenhagen, Denmark Rigshosp Blegdamsvej 9 Copenhagen Denmark DK-2100 nhagen, Denmark
Citazione:
C. Koch et al., "Presence of cystic fibrosis-related diabetes mellitus is tightly linked topoor lung function in patients with cystic fibrosis: Data from the European Epidemiologic Registry of Cystic Fibrosis", PEDIAT PULM, 32(5), 2001, pp. 343-350

Abstract

Data derived from a cross-sectional analysis of 7,566 patients stratified into six age groups were used to compare lung function, body mass index (BMI), and weight for age in patients with and without cystic fibrosis-relateddiabetes mellitus (CFDM). The presence of CFDM was tightly linked to poor lung function, regardless of age. The mean value of FEV1 % predicted in the age groups < 10, 10-< 15,15-< 20, 20-< 25, 25-< 30, and 30 years or older were 87%, 77%, 69%, 58%, 55%, and 53% in the nondiabetic cystic fibrosis (CF) patients as compared to 79%, 66%, 55%, 49%, 46%, and 44% in the diabetic CF patients. BMI and weight for age were also lower in diabetic than nondiabetic CF patients in allage groups, except for BMI in the youngest patients. The difference in lung function and in nutritional parameters between diabetic and nondiabetic CF patients was not linked to presence or absence of any specific pathogen in the lower respiratory tract. These results confirm and extend those of earlier studies in smaller numbers of patients, and they clearly identify CFDM as a powerful determinant ofsevere lung disease and reduced survival in patients with CF and diabetis mellitus. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/02/20 alle ore 03:03:42