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Titolo:
Latrogenic cardiopulmonary arrest during pediatric sedation with meperidine, promethazine, and chlorpromazine
Autore:
Brown, ET; Corbett, SW; Green, SM;
Indirizzi:
Adventist Med Ctr, Dept Emergency Med, Portland, OR USA Adventist Med CtrPortland OR USA , Dept Emergency Med, Portland, OR USA
Titolo Testata:
PEDIATRIC EMERGENCY CARE
fascicolo: 5, volume: 17, anno: 2001,
pagine: 351 - 353
SICI:
0749-5161(200110)17:5<351:LCADPS>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEDICATION ERRORS; EMERGENCY;
Keywords:
conscious sedation; DPT; MPC; adverse events; overdose;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Corbett, SW Loma Linda Univ, Med Ctr A108, Dept Emergency Med, 11234 Anderson St, LomaLinda, CA 92354 USA Loma Linda Univ 11234 Anderson St Loma Linda CA USA 92354 USA
Citazione:
E.T. Brown et al., "Latrogenic cardiopulmonary arrest during pediatric sedation with meperidine, promethazine, and chlorpromazine", PEDIAT EMER, 17(5), 2001, pp. 351-353

Abstract

The pediatric sedative combination of meperidine, promethazine, and chlorpromazine (MPC) has been widely used for more than 40 years. Despite its relatively poor efficacy and questionable safety profile, many emergency departments (EDs) continue to stock specially formulated mixtures of these threeagents. We report a case of iatrogenic cardiac arrest in a 2-month-old infant in whom a consulting resident administered too much MPC (10 times the expected dose) by the wrong route (intravenous instead of intramuscular). The child was successfully resuscitated with no apparent neurologic deficit. Subsequently, we have removed MPC entirely from our ED and instituted a policy restricting ED procedural sedation privileges to emergency physicians. We urge other EDs to do likewise.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 18:15:07