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Titolo:
The induction of BDNF and c-fos mRNA in the hippocampal formation after febrile seizures
Autore:
Kim, YH; Rhyu, IJ; Park, KW; Eun, BL; Kim, YI; Rha, HK; Kim, DS; Jo, YH; Whang, KT; Kim, MS;
Indirizzi:
Catholic Univ Korea, Coll Med, Dept Physiol, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Catholic Univ Korea, Coll Med, Dept Pediat, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Catholic Univ Korea, Coll Med, Dept Neurol, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Catholic Univ Korea, Coll Med, Dept Neurosurg, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Catholic Univ Korea, Coll Med, Catholic Neurosci Ctr, Seoul 137701, South Korea Catholic Univ Korea Seoul South Korea 137701 , Seoul 137701, South Korea Korea Univ, Coll Med, Dept Anat, Seoul 136701, South Korea Korea Univ Seoul South Korea 136701 Dept Anat, Seoul 136701, South Korea Korea Univ, Coll Med, Dept Neurol, Seoul 136701, South Korea Korea Univ Seoul South Korea 136701 pt Neurol, Seoul 136701, South Korea Korea Univ, Coll Med, Dept Pediat, Seoul 136701, South Korea Korea Univ Seoul South Korea 136701 pt Pediat, Seoul 136701, South Korea
Titolo Testata:
NEUROREPORT
fascicolo: 15, volume: 12, anno: 2001,
pagine: 3243 - 3246
SICI:
0959-4965(20011029)12:15<3243:TIOBAC>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RNA EXPRESSION; IMMATURE RAT MODEL; NEUROTROPHIC FACTOR; GENE-EXPRESSION; DENTATE GYRUS; BRAIN; EPILEPSY; PLASTICITY; PATTERNS; INJURY;
Keywords:
BDNF mRNA; c-fos mRNA; dentate gyrus; febrile seizure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Kim, MS Catholic Univ Korea, Coll Med, Dept Physiol, 505 Banpo Dong, Seoul137701,South Korea Catholic Univ Korea 505 Banpo Dong Seoul South Korea 137701 Korea
Citazione:
Y.H. Kim et al., "The induction of BDNF and c-fos mRNA in the hippocampal formation after febrile seizures", NEUROREPORT, 12(15), 2001, pp. 3243-3246

Abstract

In this study we investigated the expression of brain-derived neurotrophicfactor (BDNF) and c-fos mRNA in the hippocampal formation after febrile seizures (FSs) with in situ hybridization histochemistry using riboprobes. The induction of BDNF mRNA was firstly observed in the dentate gyrus at 30 min after FSs. The expression in the dentate gyrus peaked at 3 h and returnedto basal level at 24 h. It was also observed in the CA3 of hippocampus from 2 to 3 h. The induction of c-fos mRNA was observed in the dentate gyrus at 30 min and I h. These observations suggest that BDNF and c-fos are the genes whose expression can be altered by FSs and might be related to pathologic alterations after FSs. NeuroReport 12:3243-3246 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 01:06:39