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Titolo:
C-terminal flanking peptide of neuropeptide Y in DRG following nerve compression
Autore:
Widerberg, A; Kanje, M; Dahlin, LB;
Indirizzi:
Malmo Univ Hosp, Dept Hand Surg, SE-20502 Malmo, Sweden Malmo Univ Hosp Malmo Sweden SE-20502 Hand Surg, SE-20502 Malmo, Sweden Lund Univ, Dept Anim Physiol, Lund, Sweden Lund Univ Lund SwedenLund Univ, Dept Anim Physiol, Lund, Sweden
Titolo Testata:
NEUROREPORT
fascicolo: 15, volume: 12, anno: 2001,
pagine: 3193 - 3196
SICI:
0959-4965(20011029)12:15<3193:CFPONY>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY AFFERENT NEURONS; RABBIT VAGUS NERVE; SENSORY NEURONS; AXONAL-TRANSPORT; SCIATIC-NERVE; SPINAL-CORD; IMMUNOREACTIVITY; TRANSECTION; EXPRESSION; INHIBITION;
Keywords:
C-terminal flanking peptide of neuropeptide Y (CPON); nerve compression; nerve injury; neuron; neuropeptide Y; NPY; tourniquet;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Widerberg, A Malmo Univ Hosp, Dept Hand Surg, SE-20502 Malmo, Sweden MalmoUniv Hosp Malmo Sweden SE-20502 E-20502 Malmo, Sweden
Citazione:
A. Widerberg et al., "C-terminal flanking peptide of neuropeptide Y in DRG following nerve compression", NEUROREPORT, 12(15), 2001, pp. 3193-3196

Abstract

The C-terminal flanking peptide of neuropeptide Y (CPON) was studied in dorsal root ganglia (DRG) by immunocytochemistry after different recovery periods (3, 6,14 and 28 days) following tourniquet compression of the rat hindlimb (sciatic nerve; 150 or 300 mmHg; 2 h). Compression induced a transientincrease in the number of CPON-positive DRG-neurons (the contralateral uninjured side was devoid of CPON-positive cells). The compression-induced increase in CPON was less than that observed in separate rats subjected to sciatic nerve transection. The results show that compression induces regenerative changes in peripheral neurons and that such an injury of the nerve trunk is not limited to the site of the compression but results in the activation of the entire neuron. NeuroReport 12:3193-3196 (C) 2001 Lippincott Williams & Wilkins.

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Documento generato il 05/04/20 alle ore 06:01:46