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Titolo:
The many roles of an RNA editor
Autore:
Keegan, LP; Gallo, A; OConnell, MA;
Indirizzi:
Western Gen Hosp, Human Genet Unit, MRC, Edinburgh EH4 2XU, Midlothian, Scotland Western Gen Hosp Edinburgh Midlothian Scotland EH4 2XU dlothian, Scotland
Titolo Testata:
NATURE REVIEWS GENETICS
fascicolo: 11, volume: 2, anno: 2001,
pagine: 869 - 878
SICI:
1471-0056(200111)2:11<869:TMROAR>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
B MESSENGER-RNA; DOUBLE-STRANDED-RNA; CYTIDINE DEAMINASE AID; DSRNA-ADENOSINE-DEAMINASE; HUMAN EDITING ENZYME; APOLIPOPROTEIN-B; MOLECULAR-CLONING; BINDING DOMAIN; GLUR-B; Z-DNA;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
121
Recensione:
Indirizzi per estratti:
Indirizzo: O'Connell, MA Western Gen Hosp, Human Genet Unit, MRC, Crewe Rd, EdinburghEH4 2XU, Midlothian, Scotland Western Gen Hosp Crewe Rd Edinburgh Midlothian Scotland EH4 2XU
Citazione:
L.P. Keegan et al., "The many roles of an RNA editor", NAT REV GEN, 2(11), 2001, pp. 869-878

Abstract

The availability of complete genome sequences has made it clear that gene number is not the sole determinant of the complexity of the proteome. Additional complexity that is not readily detected by genome analysis is presentin the number and types of RNA transcript that can be derived from each locus. Although alternative splicing is a well-recognized method of generating diversity, the more subtle mechanism of RNA editing is less familiar.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 13:55:07