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Titolo:
Gene structure of the human DDX3 and chromosome mapping of its related sequences
Autore:
Kim, YS; Lee, SG; Park, SH; Song, K;
Indirizzi:
Univ Ulsan, Coll Med, Dept Biochem, Seoul 138736, South Korea Univ Ulsan Seoul South Korea 138736 t Biochem, Seoul 138736, South Korea Asan Inst Life Sci, Seoul 138736, South Korea Asan Inst Life Sci Seoul South Korea 138736 i, Seoul 138736, South Korea Korea Univ, Coll Med, Dept Anat, Seoul 136705, South Korea Korea Univ Seoul South Korea 136705 Dept Anat, Seoul 136705, South Korea
Titolo Testata:
MOLECULES AND CELLS
fascicolo: 2, volume: 12, anno: 2001,
pagine: 209 - 214
SICI:
1016-8478(20011031)12:2<209:GSOTHD>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEAD-BOX PROTEIN; PUTATIVE RNA HELICASE; MOUSE ERYTHROID-CELLS; MESSENGER-RNA; HUMAN HOMOLOG; FAMILY; YEAST; IDENTIFICATION; EXPRESSION; INTERACTS;
Keywords:
chromosomal localization; DDX3; genomic organization; pseudogenes;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Song, K Univ Ulsan, Coll Med, Dept Biochem, Seoul 138736, South Korea UnivUlsan Seoul South Korea 138736 m, Seoul 138736, South Korea
Citazione:
Y.S. Kim et al., "Gene structure of the human DDX3 and chromosome mapping of its related sequences", MOL CELLS, 12(2), 2001, pp. 209-214

Abstract

The human DDX3 gene (GenBank accession No. U50553) is the human homologue of the mouse Ddx3 gene and is a member of the gene family that contains DEAD motifs. Previously, we mapped the gene to the Xp11.3-11.23 [Park et al. (1998)]. In this report, we describe the structural organization of the human DDX3 gene. It consisted of 17 exons that span approximately 16 kb. An Aluelement was present in the intron 13. Its organization was the same as that of the human DBY gene, a closely related sequence present on the Y chromosome. We also identified two processed pseudogenes (DDX3) with a sequence that is highly homologous to those of DDX3 cDNAs, but contain a translation termination codon within its open-reading frame. Pseudogenes are mapped on human chromosomes 4 and X, respectively. In this paper, we discuss the relationships between DDX3 and its related sequences that have been isolated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 16/07/20 alle ore 19:19:59