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Titolo:
Influence of estrogens and oxytocin on germ cells death in the neonatal mammalian ovary
Autore:
De Pol, A; Benelli, A; Arletti, R; Cavazzuti, E; Sena, P; Vaccina, F; Marzona, L;
Indirizzi:
Dipt Sci Morfol Med Legali, I-41100 Modena, Italy Dipt Sci Morfol Med Legali Modena Italy I-41100 i, I-41100 Modena, Italy
Titolo Testata:
MOLECULAR, CELLULAR AND DEVELOPMENTAL BIOLOGY OF REPRODUCTION
, volume: 8, anno: 2001,
pagine: 233 - 239
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACELLULAR CALCIUM; APOPTOSIS; ACTIVATION; RAT;
Keywords:
mammalian ovary; germ cells; apoptosis; ultrastructure; estrogens; oxytocin;
Tipo documento:
Article
Natura:
Collana
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: De Pol, A Dipt Sci Morfol Med Legali, Via Pozzo 71, I-41100 Modena, Italy Dipt Sci Morfol Med Legali Via Pozzo 71 Modena Italy I-41100 ly
Citazione:
A. De Pol et al., "Influence of estrogens and oxytocin on germ cells death in the neonatal mammalian ovary", MA MA SY SE, 8, 2001, pp. 233-239

Abstract

During mammalian oogenesis, some processes involve proliferation and others drastic reduction of germ cells. This study reports on the role played by two hormones, estradiol monobenzoate and oxytocin, in the control of the number of germ cells in the neonatal mouse ovary. Female neonatal mice were treated with doses ranging between0.1 and 1 mug/mouse of estradiol monobenzoate or oxytocin and sacrificed at 5 days of postnatal age. The results showed that in the animals treated with estrogen, follicular development was more advanced than that of controls. Further the number of germ cells in apoptosis was drastically reduced. In the animals treated with oxytocin, the follicular development was arrested at the stage of primary follicles. In addition, the number of apoptoticgerm cells increased if compared with that of the controls.

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Documento generato il 02/12/20 alle ore 04:58:33