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Titolo:
MOVEMENT-DISORDERS AND MITOCHONDRIAL DYSFUNCTION
Autore:
HANNA MG; BHATIA KP;
Indirizzi:
UNIV LONDON,DEPT CLIN NEUROL,INST NEUROL,NEUROGENET SECT,QUEEN SQ LONDON WC1N 3BG ENGLAND UNIV LONDON,DEPT CLIN NEUROL,INST NEUROL,NEUROGENET SECT LONDON WC1N 3BG ENGLAND UNIV LONDON,INST NEUROL,DEPT CLIN NEUROL,MOVEMENT DISORDERS SECT LONDON ENGLAND
Titolo Testata:
Current opinion in neurology
fascicolo: 4, volume: 10, anno: 1997,
pagine: 351 - 356
SICI:
1350-7540(1997)10:4<351:MAMD>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEREDITARY OPTIC NEUROPATHY; BILATERAL STRIATAL NECROSIS; COMPLEX-I DEFICIENCY; RED FIBERS MERRF; MYOCLONIC EPILEPSY; PARKINSONS-DISEASE; RESPIRATORY-CHAIN; POINT MUTATION; DNA MUTATION; LEIGHS SYNDROME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
56
Recensione:
Indirizzi per estratti:
Citazione:
M.G. Hanna e K.P. Bhatia, "MOVEMENT-DISORDERS AND MITOCHONDRIAL DYSFUNCTION", Current opinion in neurology, 10(4), 1997, pp. 351-356

Abstract

Primary defects of mitochondrial DNA leading to respiratory chain dysfunction have been described in association with dystonia, chorea and parkinsonism. Myoclonus remains the commonest movement disorder associated with such defects. The genetic basis of Leigh's syndrome, which is frequently associated with movement disorders, may be mitochondrial or nuclear. Respiratory chain dysfunction has been identified in Huntington's disease in addition to Parkinson's disease, but the cause and relationship of this dysfunction to the pathogenesis of these common disorders is not yet determined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 13:44:24