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Titolo:
Vasoactive treatment for hearing preservation in acoustic neuroma surgery
Autore:
Strauss, C; Bischoff, B; Neu, M; Berg, M; Fahlbusch, R; Romstock, J;
Indirizzi:
Univ Erlangen Nurnberg, Dept Neurosurg, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany Univ Erlangen Nurnberg, Dept Otorhinolaryngol, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Erlangen Germany D-91054 -91054 Erlangen, Germany
Titolo Testata:
JOURNAL OF NEUROSURGERY
fascicolo: 5, volume: 95, anno: 2001,
pagine: 771 - 777
SICI:
0022-3085(200111)95:5<771:VTFHPI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBELLOPONTINE ANGLE SURGERY; AUDITORY EVOKED-POTENTIALS; HYDROXYETHYL STARCH; COCHLEAR NERVE; FACIAL-NERVE; NIMODIPINE; COAGULATION; RAT; HEMODILUTION; NEURINOMAS;
Keywords:
vasoactive therapy; nimodipine; hydroxyethyl starch; acoustic neuroma; brainstem auditory evoked potential; delayed hearing loss; hearing preservation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Strauss, C Univ Erlangen Nurnberg, Dept Neurosurg, Schwabachanlage 6, D-91054 Erlangen, Germany Univ Erlangen Nurnberg Schwabachanlage 6 Erlangen Germany D-91054
Citazione:
C. Strauss et al., "Vasoactive treatment for hearing preservation in acoustic neuroma surgery", J NEUROSURG, 95(5), 2001, pp. 771-777

Abstract

Object. Delayed hearing loss following surgery for acoustic neuroma indicates anatomical and functional preservation of the cochlear nerve and implies that a pathophysiological mechanism is initiated during surgery and continues thereafter. Intraoperative brainstem auditory evoked potentials (BAEPs) typically demonstrate gradual reversible loss of components in these patients. Methods. Based on this BAEP pattern, a consecutive series of 41 patients with unilateral acoustic neuromas was recruited into a prospective randomized study to investigate hearing outcomes following the natural postoperativecourse and recuperation after vasoactive medication. Both groups were comparable in patient age, tumor size, and preoperative hearing level. Twenty patients did not receive postoperative medical treatment. In 70% of these patients anacusis was documented and in 30% hearing was preserved. Twenty-onepatients were treated with hydroxyethyl starch and nimodipine for an average of 9 days. In 66.6% of these patients hearing was preserved and in 33.3%anacusis occurred. Conclusions. These results are statistically significant (p < 0.05, chi (2) = 5.51) and provide evidence that these surgically treated patients suffer from a disturbed microcirculation that causes delayed hearing loss following removal of acoustic neuromas.

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Documento generato il 23/10/20 alle ore 12:26:39