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Titolo:
Sex determining genes and sexual differentiation in a marsupial
Autore:
Pask, A; Renfree, MB;
Indirizzi:
Univ Melbourne, Dept Zool, Parkville, Vic 3010, Australia Univ Melbourne Parkville Vic Australia 3010 arkville, Vic 3010, Australia
Titolo Testata:
JOURNAL OF EXPERIMENTAL ZOOLOGY
fascicolo: 6, volume: 290, anno: 2001,
pagine: 586 - 596
SICI:
0022-104X(20011101)290:6<586:SDGASD>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
MULLERIAN-INHIBITING SUBSTANCE; SRY-RELATED GENE; ATR-X SYNDROME; TAMMAR WALLABY; POUCH YOUNG; CAMPOMELIC DYSPLASIA; MACROPUS-EUGENII; Y-CHROMOSOME; GONADAL DEVELOPMENT; UROGENITAL SYSTEM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
72
Recensione:
Indirizzi per estratti:
Indirizzo: Pask, A Univ Melbourne, Dept Zool, Parkville, Vic 3010, Australia Univ Melbourne Parkville Vic Australia 3010 , Vic 3010, Australia
Citazione:
A. Pask e M.B. Renfree, "Sex determining genes and sexual differentiation in a marsupial", J EXP ZOOL, 290(6), 2001, pp. 586-596

Abstract

The role of genes in the differentiation of the testis and ovary has been extensively studied in the human and the mouse. Despite over a decade of investigations, the precise roles of genes and their interactions in the pathway of sex determination are still unclear. We have chosen to take a comparative look at sex determination and differentiation to gain insights into the evolution and the conserved functions of these genes. To achieve this, we have examined a wide variety of eutherian sex determining genes in a marsupial, the tammar wallaby, to determine which genes have a conserved and fundamental mammalian sex determining role. These investigations have provided many unique insights. Here, we review the recent molecular and endocrine investigations into sexual development in marsupials, and highlight how these studies have shed light on the roles of genes and hormones in mammalian sex determination and differentiation. J. Exp. Zool. 290:586-596, 2001. (C)2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/07/20 alle ore 09:23:53