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Titolo:
Smaller, stiffer coronary bypass can moderate or reverse the adverse effects of wave reflections
Autore:
Alderson, H; Zamir, M;
Indirizzi:
Univ Western Ontario, Dept Appl Math, London, ON N6A 5B7, Canada Univ Western Ontario London ON Canada N6A 5B7 London, ON N6A 5B7, Canada Univ Western Ontario, Dept Med Biophys, London, ON N6A 5C1, Canada Univ Western Ontario London ON Canada N6A 5C1 London, ON N6A 5C1, Canada
Titolo Testata:
JOURNAL OF BIOMECHANICS
fascicolo: 11, volume: 34, anno: 2001,
pagine: 1455 - 1462
SICI:
0021-9290(200111)34:11<1455:SSCBCM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
FLOW-THROUGH; HYPERPLASIA; LOOP;
Keywords:
coronary bypass; wave reflections; hemodynamics; pulsatile flow;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Zamir, M Univ Western Ontario, Dept Appl Math, London, ON N6A 5B7, Canada Univ Western Ontario London ON Canada N6A 5B7 ON N6A 5B7, Canada
Citazione:
H. Alderson e M. Zamir, "Smaller, stiffer coronary bypass can moderate or reverse the adverse effects of wave reflections", J BIOMECHAN, 34(11), 2001, pp. 1455-1462

Abstract

The question of whether the mechanical stiffness of a coronary bypass or that of a diseased coronary artery can have a significant effect on the hemodynamics in these vessels is addressed analytically, with emphasis on the effects of wave reflections. The analysis is based on a model of the vesselsinvolved, and the results show the essential hemodynamic effects in each vessel. It is found that in the absence of a bypass graft, wave reflections resulting from a narrowing and stiffening of a diseased coronary artery have the effect of actually aiding the flow in the diseased vessel. In the presence of a bypass graft, however, the effects of wave reflections are reversed and become adverse to flow in both the bypass graft and the diseased coronary artery. A stiffer bypass moderates these effects and is therefore preferable to a more elastic bypass. The adverse effects also depend critically on the relative diameter of the bypass. Here the results indicate that abypass of smaller diameter than that of the native coronary artery can moderate and even reverse the adverse effects of wave reflections resulting from the presence of the bypass. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 19:23:42