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Titolo:
Proximal Crohn's disease: Review of the clinicopathologic features and therapy
Autore:
van Hogezand, RA; Witte, AMC; Veenendaal, RA; Wagtmans, MJ; Lamers, CBHW;
Indirizzi:
Leiden Univ, Med Ctr, Dept Gastroenterol Hepatol, NL-2300 RC Leiden, Netherlands Leiden Univ Leiden Netherlands NL-2300 RC NL-2300 RC Leiden, Netherlands
Titolo Testata:
INFLAMMATORY BOWEL DISEASES
fascicolo: 4, volume: 7, anno: 2001,
pagine: 328 - 337
SICI:
1078-0998(200111)7:4<328:PCDROT>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
UPPER GASTROINTESTINAL-TRACT; INFLAMMATORY BOWEL-DISEASE; GRANULOMATOUS GASTRITIS; HELICOBACTER-PYLORI; ENDOSCOPIC BIOPSIES; RADIOLOGIC FINDINGS; REGIONAL ENTERITIS; CLINICAL-FEATURES; SMALL-INTESTINE; DUODENUM;
Keywords:
Crohn's disease; upper gastrointestinal Crohn's disease; stomach; esophagus; duodenum;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
107
Recensione:
Indirizzi per estratti:
Indirizzo: van Hogezand, RA Leiden Univ, Med Ctr, Dept Gastroenterol Hepatol, C4-P,POB 9600, NL-2300 RC Leiden, Netherlands Leiden Univ C4-P,POB 9600 Leiden Netherlands NL-2300 RC
Citazione:
R.A. van Hogezand et al., "Proximal Crohn's disease: Review of the clinicopathologic features and therapy", INFLAMM B D, 7(4), 2001, pp. 328-337

Abstract

Crohn's disease in the proximal region of the digestive tract is uncommon. Better diagnostically procedures and more careful histologic examination has led to a higher detection of proximal Crohn's disease. The diagnosis is based on symptoms, endoscopy with serial sections, or double contrast radiography. The most common histologic finding for this diagnosis are granulomas in the mucosa in Helicobacter pylori-negative patients, but the granulomas are not always frequently detected. Endoscopic lesions in the proximal regions look like the lesions that could be found in the distal regions. Notching in the duodenal folds could be a strong indication for Crohn's desease. Radiological lesions are not always characteristic, but should be used incombination with endoscopy. Stenosis is an important complication, but fistula formation and pseudodiverticular formation is possible. There is no uniform medical therapy, but the regular anti-inflammatory management for Crohn's disease is most often used. Sometimes surgery is needed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:47:28