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Titolo:
Liver and kidney foreign bodies granulomatosis in a patient with malocclusion, bruxism, and worn dental prostheses
Autore:
Ballestri, M; Baraldi, A; Gatti, AM; Furci, L; Bagni, A; Loria, P; Rapana, RM; Carulli, N; Albertazzi, A;
Indirizzi:
Univ Modena, Dept Nephrol Dialysis & Transplantat, I-41100 Modena, Italy Univ Modena Modena Italy I-41100 s & Transplantat, I-41100 Modena, Italy Univ Modena, Lab Biomat, I-41100 Modena, Italy Univ Modena Modena Italy I-41100 dena, Lab Biomat, I-41100 Modena, Italy Univ Modena, Dept Morphol Sci & Forens Med, I-41100 Modena, Italy Univ Modena Modena Italy I-41100 Sci & Forens Med, I-41100 Modena, Italy Univ Modena, Dept Internal Med, I-41100 Modena, Italy Univ Modena ModenaItaly I-41100 ept Internal Med, I-41100 Modena, Italy
Titolo Testata:
GASTROENTEROLOGY
fascicolo: 5, volume: 121, anno: 2001,
pagine: 1234 - 1238
SICI:
0016-5085(200111)121:5<1234:LAKFBG>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIP-ARTHROPLASTY; REPLACEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Ballestri, M Policlin Modena, Via Pozzo 71, I-41100 Modena, Italy PoliclinModena Via Pozzo 71 Modena Italy I-41100 ena, Italy
Citazione:
M. Ballestri et al., "Liver and kidney foreign bodies granulomatosis in a patient with malocclusion, bruxism, and worn dental prostheses", GASTROENTY, 121(5), 2001, pp. 1234-1238

Abstract

Granulomatous reactions caused by foreign bodies have been described in drug abusers, in subjects exposed to occupational pollutants, and more rarely, in association with the use of prosthetic devices. We describe a 62-year-old patient with multiorgan parenchymal granulomatosis caused by inorganic debris of unknown origin. The patient presented with fever, hepatosplenomegaly, progressive cholestasis, and acute renal failure. Liver and kidney biopsies showed the presence of noncaseating epithelioid giant-cell granulomas-containing scattered polarizable particles. Similar particles were also present in stools. Studies by innovative scanning electron microscopy and energy-dispersive microanalytical techniques showed that the particles isolated in liver, kidney, and stools were made by feldspars, the main, component of porcelain. No occupational or environmental exposure to these materials could be identified in this patient and the only reliable source of the porcelain debris turned out to be constituted by 2 dental bridges evidently worn because of a possible inappropriate construction, malocclusion, and bruxism. The porcelain of the dental prostheses had the same elemental spectrumof the particles isolated from stool specimens and liver-kidney granuloma. After identification of the dental. prostheses as the most likely source of ceramic debris, and after their removal, the particles from stool specimens disappeared. The patient was then treated with steroids leading to a remission of the clinical symptoms and a decrease in granulomatous inflammatory reaction. in both liver and kidney. This is the first report suggesting that a foreign body systemic granulomatosis can be associated with worn dental prostheses.

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Documento generato il 29/11/20 alle ore 02:26:30