Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A diet containing rapeseed oil-based fats does not increase lipid peroxidation in humans when compared to a diet rich in saturated fatty acids
Autore:
Sodergren, E; Gustafsson, IB; Basu, S; Nourooz-Zadeh, J; Nalsen, C; Turpeinen, A; Berglund, L; Vessby, B;
Indirizzi:
Uppsala Univ, Dept Publ Hlth & Caring Sci, Sect Geriatr Clin Nutr Res, Uppsala, Sweden Uppsala Univ Uppsala Sweden Sect Geriatr Clin Nutr Res, Uppsala, Sweden Univ Orebro, Dept Culinary Arts, Orebro, Sweden Univ Orebro Orebro Sweden iv Orebro, Dept Culinary Arts, Orebro, Sweden Univ Coll London, Dept Med, Div Med, London, England Univ Coll London London England don, Dept Med, Div Med, London, England Univ Helsinki, Div Nutr, Dept Appl Chem & Microbiol, Helsinki, Finland Univ Helsinki Helsinki Finland Appl Chem & Microbiol, Helsinki, Finland
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL NUTRITION
fascicolo: 11, volume: 55, anno: 2001,
pagine: 922 - 931
SICI:
0954-3007(200111)55:11<922:ADCROF>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; LIPOPROTEIN CHOLESTEROL CONCENTRATIONS; LOW-DENSITY LIPOPROTEINS; HEALTHY-SUBJECTS; VITAMIN-E; IN-VIVO; LINOLEIC-ACID; SUNFLOWER OIL; CANOLA OIL; OXIDATIVE MODIFICATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Sodergren, E Uppsala Univ, Dept Publ Hlth & Caring Sci, Sect Geriatr Clin Nutr Res, Uppsala, Sweden Uppsala Univ Uppsala Sweden Clin Nutr Res, Uppsala, Sweden
Citazione:
E. Sodergren et al., "A diet containing rapeseed oil-based fats does not increase lipid peroxidation in humans when compared to a diet rich in saturated fatty acids", EUR J CL N, 55(11), 2001, pp. 922-931

Abstract

Objective: To compare the effects of a rapeseed oil-based diet containing an increased proportion of easily oxidised polyunsaturated fatty acids suchas alpha -linolenic acid with a diet rich in saturated fatty acids on the degree of lipid peroxidation in the human body. Design: A randomised cross-over study. Subjects and interventions: Nineteen healthy moderately hyperlipidemic subjects (six women and 13 men, age 50 +/- 8 y and body mass index (BMI) 24.5 /- 2.6 kg/m(2)) were given a rapeseed oil-based diet (RO) and a control diet (SAT) rich in saturated fatty acids during two consecutive 4 week periods separated by a 4 week wash-out period. Biomarkers of lipid peroxidation and antioxidants were analysed in plasma and urine. Results: No significant differences in plasma or urinary levels of free 8-iso-prostaglandin F-2 alpha, plasma total 8-iso-prostaglandin F-2 alpha plasma hydroperoxides or plasma malondialdehyde were observed between the RO and SAT diets (P = 0.14 - 0.95). A higher concentration of serum gamma -tocopherol was detected after the RO diet compared to the SAT diet (P < 0.001),whereas the serum alpha -tocopherol concentration and plasma antioxidativecapacity did not differ between the two test diets. The total cholesterol,LDL cholesterol and LDL/HDL ratio were lower after the RO diet compared tothe SAT diet (P < 0.001), while HDL cholesterol and total triglyceride levels were similar after the two diets. Conclusion: These results suggest that a rapeseed oil-based diet rich in alpha -linolenic acid does not seem to increase the degree of lipid peroxidation in plasma and urine compared to a diet rich in saturated fats. This ispossibly due to a sufficient content of antioxidants in the rapeseed oil diet to increase circulating concentrations or antioxidants that may protectunsaturated fatty acids from oxidation. Sponsorship: Swedish Council for Forestry and Agricultural Research and Foundation for Geriatric Research. Descriptors: rapeseed oil; lipid peroxidation, antioxidants, serum lipids.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 04:08:05