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Titolo:
Fat consumption and HbA(1c) levels - The EPIC-Norfolk Study
Autore:
Harding, AH; Sargeant, LA; Welch, A; Oakes, S; Luben, RN; Bingham, S; Day, NE; Khaw, KT; Wareham, NJ;
Indirizzi:
Univ Cambridge, Inst Publ Hlth, Dept Publ Hlth & Primary Care, Cambridge CB2 2SR, England Univ Cambridge Cambridge England CB2 2SR are, Cambridge CB2 2SR, England
Titolo Testata:
DIABETES CARE
fascicolo: 11, volume: 24, anno: 2001,
pagine: 1911 - 1916
SICI:
0149-5992(200111)24:11<1911:FCAHL->2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMPAIRED GLUCOSE-TOLERANCE; FOOD FREQUENCY QUESTIONNAIRE; DEPENDENT DIABETES-MELLITUS; HABITUAL DIETARY-INTAKE; CORONARY HEART-DISEASE; FOLLOW-UP; GLYCATED HEMOGLOBIN; INSULIN SENSITIVITY; PHYSICAL-ACTIVITY; ENERGY-INTAKE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Wareham, NJ Univ Cambridge, Inst Publ Hlth, Dept Publ Hlth & Primary Care,Robinson Way, Cambridge CB2 2SR, England Univ Cambridge Robinson Way Cambridge England CB2 2SR England
Citazione:
A.H. Harding et al., "Fat consumption and HbA(1c) levels - The EPIC-Norfolk Study", DIABET CARE, 24(11), 2001, pp. 1911-1916

Abstract

OBJECTIVE - To describe the relationship between total dietary fat and thepattern Of Fat intake and HbA(1c). RESEARCH DESIGN AND METHODS - in this cross-sectional study, 2,759 men and3,464 women (40-78 years of age) without a previous diagnosis of type 2 diabetes were recruited from a population-based sampling frame. Diet was assessed using a self-reported semiquantitative food frequency questionnaire. RESULTS- The HbA(1c) level was negatively associated with the polyunsaturated Fat-to-saturated fat ratio (P:S ratio) of the diet (beta = -0.0338 HbA(1c)% per SD change in RS ratio P < 0.001) and positively associated with the total level of fat intake (beta = 0.0620 HbA(1c)% per SD change in total fat intake P < 0.001), adjusted for age and total energy intake. The associations remained significant when adjusted for each other and for total energy, protein, age, sex, family history, of diabetes, BMI, waist-to-hip ratio, physical activity, and smoking (for P:S ratio, P = -0.0200 HbA(1c)% per SD change in RS ratio, P = 0.013; for total fat, beta = 0.420% HbA(1c)% per SD change in total fat intake, P < 0,001). The benefits from a high P:S ratio were attributed to a lower saturated fat intake. CONCLUSIONS - These findings demonstrate independent associations between HbA(1c) concentration across the normal range of HbA(1c) and both total fatintake and the pattern of dietary fat intake. They provide further supportto efforts promoting modifications in the intake of dietary fat.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:46:31