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Titolo:
Is there a typical pattern of brain SPECT imaging in Alzheimer's disease?
Autore:
Steinling, M; Defebvre, L; Duhamel, A; Lecouffe, P; Lavenu, I; Pasquier, F; Charpentier, P;
Indirizzi:
Univ Hosp Lille 2, CHRU Lille, Fac Med, Unit Brain Funct Imaging, Lille, France Univ Hosp Lille 2 Lille France Unit Brain Funct Imaging, Lille, France Univ Hosp Lille 2, CHRU Lille, Fac Med, Dept Neurol, Lille, France Univ Hosp Lille 2 Lille France lle, Fac Med, Dept Neurol, Lille, France Univ Hosp Lille 2, CHRU Lille, Fac Med, Ctr Etud & Rech Informat Med, Lille, France Univ Hosp Lille 2 Lille France Etud & Rech Informat Med, Lille, France
Titolo Testata:
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS
fascicolo: 6, volume: 12, anno: 2001,
pagine: 371 - 378
SICI:
1420-8008(200111/12)12:6<371:ITATPO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHOTON-EMISSION TOMOGRAPHY; CEREBRAL BLOOD-FLOW; LEWY-BODY-DISEASE; FRONTOTEMPORAL DEMENTIA; HETEROGENEITY; DEGENERATION; DIAGNOSIS; TC-99M; CONSENSUS; CRITERIA;
Keywords:
single-photon emission computed tomography positron emission tomography; neurodegenerative dementia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Steinling, M Ctr Hosp Reg & Univ Lille, Serv Cent Med Nucl, Unit Brain Funct Imaging, Hosp R Salengro, Pl Verdun, F-59037 Lille, France Ctr Hosp Reg & Univ Lille Pl Verdun Lille France F-59037 nce
Citazione:
M. Steinling et al., "Is there a typical pattern of brain SPECT imaging in Alzheimer's disease?", DEMENT G C, 12(6), 2001, pp. 371-378

Abstract

The identification of new nosological forms such as Lewy body disease (LBD) requires a re-evaluation of the patterns observed in brain functional imaging in the various forms of dementia. We studied 60 demented patients, divided into three groups and fulfilling the clinical criteria for Alzheimer'sdisease (AD), LBD and frontotemporal dementia (FTD), using Tc-HMPAO and a brain-dedicated SPECT system. After normalisation we applied a cut-off at two levels according to previously established criteria. We reaffirmed the already established data concerning FTD (mainly a bilateral frontal decrease) and for LBD (a severe diffuse decrease in the frontal regions and also inthe posterior association cortex). In contrast, the decrease in AD was strictly limited to the parieto-occipital cortex, irrespective of the severityof the cognitive decline. We hypothesise that the major simplification concerning the pattern observed in AD can be explained by the fact that patients suffering from LBD have previously been included in the groups of AD patients. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 16:59:57