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Titolo:
Reference intervals and variation for urinary epinephrine, norepinephrine and cortisol in healthy men and women in Denmark
Autore:
Hansen, AM; Garde, AH; Christensen, JM; Eller, NH; Netterstrom, B;
Indirizzi:
Natl Inst Occupat Hlth, Dept Physiol, DK-2100 Copenhagen, Denmark Natl Inst Occupat Hlth Copenhagen Denmark DK-2100 00 Copenhagen, Denmark Natl Environm Res Inst, Roskilde, Denmark Natl Environm Res Inst Roskilde Denmark onm Res Inst, Roskilde, Denmark Cent Hosp Hillerod, Dept Occupat Med, DK-3400 Hillerod, Denmark Cent Hosp Hillerod Hillerod Denmark DK-3400 d, DK-3400 Hillerod, Denmark
Titolo Testata:
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
fascicolo: 9, volume: 39, anno: 2001,
pagine: 842 - 849
SICI:
1434-6621(200109)39:9<842:RIAVFU>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BIOLOGICAL VARIATION; REFERENCE VALUES; BLOOD-CONCENTRATIONS; PSYCHOSOCIAL STRESS; CLINICAL-CHEMISTRY; CATECHOLAMINES; GENDER; WORK; TESTOSTERONE; PERFORMANCE;
Keywords:
reference interval; biological variation; urine; epinephrine; norepinephrine; cortisol;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
40
Recensione:
Indirizzi per estratti:
Indirizzo: Hansen, AM Natl Inst Occupat Hlth, Dept Physiol, Lerso Parkalle 105, DK-2100 Copenhagen, Denmark Natl Inst Occupat Hlth Lerso Parkalle 105 Copenhagen Denmark DK-2100
Citazione:
A.M. Hansen et al., "Reference intervals and variation for urinary epinephrine, norepinephrine and cortisol in healthy men and women in Denmark", CLIN CH L M, 39(9), 2001, pp. 842-849

Abstract

Reference intervals for urinary epinephrine, norepinephrine and cortisol in 120 healthy individuals performing their routine work were established according to the International Union of Pure and Applied Chemistry (IUPAC) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) for use in the risk assessment of exposure to occupational stress. Reference intervals were established for three different times of the day:in morning samples (05.45-07.15) the limit of detection (LOD) was 2.10 mu mol epinephrine/mol creatinine (82 women) and 2.86 mu mol epinephrine/mol creatinine (37 men), and the reference interval was 3.6-29.1 mu mol norepinephrine/mol creatinine and 2.3-52.8 mu mol cortisol/mol creatinine (119 women and men); in afternoon samples (15.30-18.30) the reference interval was 0.64-10.8 mu mol epinephrine/mol creatinine (82 women), 1.20-11.2 mu mol/epinephrine/mol creatinine (36 men), 11.0-54.1 mu mol/norepinephrine/mol creatinine and LOD was 42.4 mu mol cortisol/mol creatinine (117 women and men); in evening samples (21.45-23.45) LOD was 8.66 mu mol epinephrine/mol creatinine (81 women) and 7.99 mu mol/epinephrine/mol creatinine (36 men), the reference interval was 11.0-54.1 mu mol norepinephrine/mol creatinine, and LOD was 42.4 pmol cortisol/mol creatinine (117 women and men). A variance component model for describing the effects of age, body mass index (BMI), diurnal variation, gender, days of sick leave during past year and smoking habits was established. Women showed a higher morning value but excreted lower amounts of epinephrine during the day as compared to men. No gender differences could be demonstrated for the excretion of norepinephrine and cortisol. Excretion of epinephrine and norepinephrine increased with smoking and decreased with increased BMI. No effects were observed in the excretion of cortisol.

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Documento generato il 22/01/20 alle ore 12:42:44