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Titolo:
In vitro study of FFR, QCA, and IVUS for the assessment of optimal stent deployment
Autore:
Matthys, K; Carlier, S; Segers, P; Ligthart, J; Sianos, G; Serrano, P; Verdonck, PR; Serruys, PW;
Indirizzi:
State Univ Ghent, Hydraul Lab, Inst Biomed Technol IBITECH, B-9000 Ghent, Belgium State Univ Ghent Ghent Belgium B-9000 nol IBITECH, B-9000 Ghent, Belgium Ctr Thorax, Rotterdam, Netherlands Ctr Thorax Rotterdam NetherlandsCtr Thorax, Rotterdam, Netherlands
Titolo Testata:
CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS
fascicolo: 3, volume: 54, anno: 2001,
pagine: 363 - 375
SICI:
1522-1946(200111)54:3<363:IVSOFQ>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY PRESSURE MEASUREMENT; FRACTIONAL FLOW RESERVE; IN-VITRO; INTRAVASCULAR ULTRASOUND; STENOSIS SEVERITY; ARTERY STENOSIS; ANGIOPLASTY; IMPLANTATION; ANGIOGRAPHY; VALIDATION;
Keywords:
flow reserve; intravascular ultrasound; angiography; suboptimal stent deployment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Matthys, K State Univ Ghent, Hydraul Lab, Inst Biomed Technol IBITECH, Sint Pietersnieuwstr 41, B-9000 Ghent, Belgium State Univ Ghent Sint Pietersnieuwstr 41 Ghent Belgium B-9000
Citazione:
K. Matthys et al., "In vitro study of FFR, QCA, and IVUS for the assessment of optimal stent deployment", CATHET C IN, 54(3), 2001, pp. 363-375

Abstract

We tested whether fractional flow reserve (FFR) discriminates between suboptimally and optimally deployed stents. Latex tubes (diameter circle divide= 4 mm) with diameter stenosis 40% (n = 3), 50% (n = 3) and 60% (n = 3) were tested in a pulsatile flow system, using water. Measurements were done at baseline (n = 9; FFR/QCA) and after suboptimal (SOD; 3-mm balloon at 8 atm) and optimal (OD; 4 mm balloon at 16 atm) deployment of a 35-mm stent (n = 6; FFR/OCA/IVUS). Varying Q from 150 to 50 ml/min increased FFR by 2-7%. Conversely, at 100 ml/min, FFR increased by only 0.8% from SOD to OD (P < 0.05). Extrapolating data to blood flow, the gain in FFR from SOD to OD is less than 5% for Q = 100 ml/min, while FFR may increase by 15-20% by changesin blood flow from 50 to 150 ml/min. We conclude that IVUS and OCA are more appropriate for the assessment of optimal stent deployment. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 06:28:25