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Titolo:
Pulsatility of ascending aorta and restenosis after coronary angioplasty in patients > 60 years of age with stable angina pectoris
Autore:
Lu, TM; Hsu, NW; Chen, YH; Lee, WS; Wu, CC; Ding, YA; Chang, MS; Lin, SJ;
Indirizzi:
Taipei Vet Gen Hosp, Div Cardiol, Dept Med, Taipei, Taiwan Taipei Vet Gen Hosp Taipei Taiwan Div Cardiol, Dept Med, Taipei, Taiwan Natl Yang Ming Univ, Inst Clin Med, Taipei 112, Taiwan Natl Yang Ming Univ Taipei Taiwan 112 Inst Clin Med, Taipei 112, Taiwan Natl Yang Ming Univ, Cardiovasc Res Ctr, Taipei 112, Taiwan Natl Yang MingUniv Taipei Taiwan 112 iovasc Res Ctr, Taipei 112, Taiwan
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 9, volume: 88, anno: 2001,
pagine: 964 - 968
SICI:
0002-9149(20011101)88:9<964:POAAAR>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; PULSE PRESSURE; BLOOD-PRESSURE; CARDIOVASCULAR MORTALITY; AUGMENTATION; FLOW; COUNTERPULSATION; REPERFUSION; PREDICTOR; THERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Lin, SJ Taipei Vet Gen Hosp, Div Cardiol, Dept Med, 201 Sect 2,Shih Pai Rd, Taipei, Taiwan Taipei Vet Gen Hosp 201 Sect 2,Shih Pai Rd Taipei Taiwan Taiwan
Citazione:
T.M. Lu et al., "Pulsatility of ascending aorta and restenosis after coronary angioplasty in patients > 60 years of age with stable angina pectoris", AM J CARD, 88(9), 2001, pp. 964-968

Abstract

A recent study has demonstrated that the pulsatility of the ascending aorta is a strong predictive factor for restenosis after coronary angioplasty. However, whether the pulsatility of the ascending aorta is still a significant predictor for restenosis in elderly patients with a stiffer aorta is unknown. We investigated the relation between arterial pulsatility in the ascending aorta and restenosis after coronary angioplasty in patients aged >60years. Eighty-seven consecutive patients (80 men, aged 72.5 +/- 5.1, years) with stable angina were included. Before angioplasty the arterial systolic, diastolic, and mean pressure waveforms of the ascending aorta were measured. We used fractional pulse pressure (PPf, the ratio of pulse pressure tomean pressure) and pulsatility index (PI, the ratio of pulse pressure to diastolic pressure) to estimate the pulsatility of the ascending aorta. Angiographic restenosis occurred in 39 patients. Pulse pressure, PPf, and PI were significantly higher in patients with restenosis after car-nary angioplasty (restenosis vs without restenosis: pulse pressure, 77.6 +/- 12.2 vs 66.1 +/- 15.4 mm Hg [p <0.001]; PPf, 0.80 +/- 0.09 vs 0.69 +/- 0.11 [p <0.001]; PI, 1.19 +/- 0.20 vs 0.98 +/- 0.21 [p <0.001]). After multivariate stepwise adjustment of risk factors of restenosis and using receiver-operating characteristic analysis, the odds ratio (OR) of restenosis was: pulse pressure >66 mm Hg, OR 5.88 (95% confidence interval [CI] 2.17 to 15.93); PPf >0.72, OR 13.71 (95% CI 4.81 to 39.05); PI > 1.06, OR 13.56 (95% CI 4.67 to 39.38). Moreover, among patients aged >70 years (n = 60), the predictive values of PPf and PI were even higher than those in patients aged less than or equal to 70 years (n = 27). Thus, in elderly patients with stable angina, the pulsatility of the ascending aorta is a powerful predictor of restenosis after coronary angioplasty. (C)2001 by Excerpta Medica, Inc.

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Documento generato il 25/01/20 alle ore 09:30:40