Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Caffeine eliminates psychomotor vigilance deficits from sleep inertia
Autore:
Van Dongen, HPA; Price, NJ; Mullington, JM; Szuba, MP; Kapoor, SC; Dinges, DF;
Indirizzi:
Univ Penn, Sch Med, Dept Psychiat, Div Sleep & Chronobiol, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 hronobiol, Philadelphia, PA 19104 USA Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA Beth Israel Deaconess Med Ctr Boston MA USA 02215 r, Boston, MA 02215 USA Harvard Univ, Sch Med, Boston, MA USA Harvard Univ Boston MA USAHarvard Univ, Sch Med, Boston, MA USA Hosp Univ Penn, Core Lab, Gen Clin Res Ctr, Philadelphia, PA 19104 USA Hosp Univ Penn Philadelphia PA USA 19104 Ctr, Philadelphia, PA 19104 USA
Titolo Testata:
SLEEP
fascicolo: 7, volume: 24, anno: 2001,
pagine: 813 - 819
SICI:
0161-8105(20011101)24:7<813:CEPVDF>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
COGNITIVE PERFORMANCE; TIME-COURSE; WAKEFULNESS; ALERTNESS; RATS; RESTRICTION; DEPRIVATION; OPERATIONS; NIGHT; NAPS;
Keywords:
sleep inertia; awakening; caffeine; adenosine; sleep deprivation; nap sleep; function of sleep;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Van Dongen, HPA Univ Penn, Sch Med, Dept Psychiat, Div Sleep & Chronobiol,1019 Blockley Hall,423 Guardian Dr, Philadelphia, PA 19104 USA Univ Penn 1019 Blockley Hall,423 Guardian Dr Philadelphia PA USA 19104
Citazione:
H.P.A. Van Dongen et al., "Caffeine eliminates psychomotor vigilance deficits from sleep inertia", SLEEP, 24(7), 2001, pp. 813-819

Abstract

Study Objectives: This study sought to establish the effects of caffeine on sleep inertia, which is the ubiquitous phenomenon of cognitive performance impairment, grogginess and tendency to return to sleep immediately after awakening. Design: 28 normal adult volunteers were administered sustained low-dose caffeine or placebo (randomized double-blind) during the last 66 hours of an 88-hour period of extended wakefulness that included seven 2-hour naps during which polysomnographical recordings were made. Every 2 hours of wakefulness, and immediately after abrupt awakening from the naps, psychomotor vigilance performance was tested. Setting: N/AParticipants: N/AInterventions: N/AMeasurements and Results: In the placebo condition, sleep inertia was manifested as significantly impaired psychomotor vigilance upon awakening from the naps. This impairment was absent in the caffeine condition. Caffeine had only modest effects on nap sleep. Conclusions: Caffeine was efficacious in overcoming sleep inertia. This suggests a reason for the popularity of caffeine-containing beverages after awakening. Caffeine's main mechanism of action on the central nervous systemis antagonism of adenosine receptors. Thus, increased adenosine in the brain upon awakening may be the cause of sleep inertia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 12:47:31