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Titolo:
Ankle brachial pressure index in systemic sclerosis: influence of disease subtype and anticentromere antibody
Autore:
Wan, MC; Moore, T; Hollis, S; Herrick, AL;
Indirizzi:
Univ Manchester, Hope Hosp, Ctr Rheumat Dis, Salford M6 8HD, Lancs, England Univ Manchester Salford Lancs England M6 8HD lford M6 8HD, Lancs, England Univ Lancaster, Dept Math & Stat, Lancaster LA1 4WF, England Univ Lancaster Lancaster England LA1 4WF tat, Lancaster LA1 4WF, England
Titolo Testata:
RHEUMATOLOGY
fascicolo: 10, volume: 40, anno: 2001,
pagine: 1102 - 1105
SICI:
1462-0324(200110)40:10<1102:ABPIIS>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PRIMARY RAYNAUDS-PHENOMENON; MACROVASCULAR DISEASE; INCREASED PREVALENCE; SCLERODERMA; ABNORMALITIES;
Keywords:
ankle brachial pressure index; systemic sclerosis; anticentromere antibody;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Herrick, AL Univ Manchester, Hope Hosp, Ctr Rheumat Dis, Salford M6 8HD, Lancs, England Univ Manchester Salford Lancs England M6 8HD , Lancs, England
Citazione:
M.C. Wan et al., "Ankle brachial pressure index in systemic sclerosis: influence of disease subtype and anticentromere antibody", RHEUMATOLOG, 40(10), 2001, pp. 1102-1105

Abstract

Objective. To test the hypothesis that patients with limited cutaneous systemic sclerosis (SSc) have a higher incidence of lower limb large vessel disease than patients with diffuse cutaneous disease, and that anticentromereantibody is a risk factor for lower limb large vessel disease. Methods. Clinical: and laboratory data from 119, patients with SSc (91 patients with limited cutaneous disease, 28 patients with diffuse cutaneous disease) who had bilateral ankle brachial pressure indices (ABPI) measured between March 1997 and January 2000 were reviewed retrospectively. Results. There was no evidence of reduced ABPI in limited cutaneous disease (P = 0.65), average reduction 0.01 [95% confidence interval (CI) -0.04 to+0.07]. There was some suggestion of reduced ABPI in anticentromere-positive patients (P = 0.12), average reduction 0.04 (95% CI -0.01 to +0.09). Conclusions. The severity of large vessel macrovascular disease, as assessed by ABPI, is not dependent on disease subtype. Anticentromere antibody may be weakly associated with a reduction in ABPI.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/21 alle ore 03:49:18