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Titolo:
An anisotropic diffusion method for denoising dynamic susceptibility contrast-enhanced magnetic resonance images
Autore:
Murase, K; Yamazaki, Y; Shinohara, M; Kawakami, K; Kikuchi, K; Miki, H; Mochizuki, T; Ikezoe, J;
Indirizzi:
Osaka Univ, Sch Med, Dept Med Engn, Div Allied Hlth Sci, Suita, Osaka 5650871, Japan Osaka Univ Suita Osaka Japan 5650871 lth Sci, Suita, Osaka 5650871, Japan Ehime Univ, Sch Med, Dept Radiol, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan
Titolo Testata:
PHYSICS IN MEDICINE AND BIOLOGY
fascicolo: 10, volume: 46, anno: 2001,
pagine: 2713 - 2723
SICI:
0031-9155(200110)46:10<2713:AADMFD>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; HIGH-RESOLUTION MEASUREMENT; TRACER BOLUS PASSAGES; MRI; PERFUSION; VOLUME; DESIGN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Murase, K Osaka Univ, Sch Med, Dept Med Engn, Div Allied Hlth Sci, 1-7 Yamadaoka, Suita, Osaka 5650871, Japan Osaka Univ 1-7 Yamadaoka Suita Osaka Japan 5650871 650871, Japan
Citazione:
K. Murase et al., "An anisotropic diffusion method for denoising dynamic susceptibility contrast-enhanced magnetic resonance images", PHYS MED BI, 46(10), 2001, pp. 2713-2723

Abstract

The purpose of this study was to present an application of a novel denoising technique for improving the accuracy of cerebral blood flow (CBF) imagesgenerated from dynamic susceptibility contrast-enhanced magnetic resonanceimaging (DSC-MRI). The method presented in this study was based on anisotropic diffusion (AD). The usefulness of this method was firstly investigatedusing computer simulations. We applied this method to patient data acquired using a 1.5 T MR system. After a bolus injection of Gd-DTPA, we obtained 40-50 dynamic images with a 1.32-2.08 s time resolution in 4-6 slices. The dynamic images were processed using the AD method, and then the CBF images were generated using pixel-by-pixel deconvolution analysis. For comparison,the CBF images were also generated with or without processing the dynamic images using a median or Gaussian filter. In simulation studies, the standard deviation of the CBF values obtained after processing by the AD method was smaller than that of the CBF values obtained without any processing. while the mean value agreed well with the true CBF value. Although the median and Gaussian filters also reduced image noise, the mean CBF values were considerably underestimated compared with the true values. Clinical studies also suggested that the AD method was capable of reducing the image noise while preserving the quantitative accuracy of CBF images. In conclusion, the AD method appears useful for denoising DSC-MRI. which will make the CBF images generated from DSC-MRI more reliable.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:48:56