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Titolo:
Novel peptidomimetics of the antifungal cyclic peptide rhodopeptin: Designof mimetics utilizing scaffolding methodology
Autore:
Nakayama, K; Kawato, HC; Inagaki, H; Ohta, T;
Indirizzi:
Daiichi Pharmaceut Co Ltd, Med Chem Res lab, Edogawa Ku, Tokyo 1348630, Japan Daiichi Pharmaceut Co Ltd Tokyo Japan 1348630 a Ku, Tokyo 1348630, Japan
Titolo Testata:
ORGANIC LETTERS
fascicolo: 22, volume: 3, anno: 2001,
pagine: 3447 - 3450
SICI:
1523-7060(20011101)3:22<3447:NPOTAC>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-D-GLUCOSE; RHODOCOCCUS SP; TETRAPEPTIDES; ANALOGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Nakayama, K Daiichi Pharmaceut Co Ltd, Med Chem Res lab, Edogawa Ku, 1-16-13 Kitakasi,Tokyo 1348630, Japan Daiichi Pharmaceut Co Ltd 1-16-13 KitakasiTokyo Japan 1348630
Citazione:
K. Nakayama et al., "Novel peptidomimetics of the antifungal cyclic peptide rhodopeptin: Designof mimetics utilizing scaffolding methodology", ORG LETT, 3(22), 2001, pp. 3447-3450

Abstract

[GRAPHICS]Novel nonpeptide peptidomimetics of the antifungal cyclic peptide Rhodopeptin were designed utilizing hydantoin, benzimidazole, D-glucosamine, quinolone, and benzodiazepine units as scaffolds. The scaffolds were chosen on the basis of their potential to improve the physiochemical properties of the peptidomimetics as well as their ability to bear the requisite Rhodopeptin side-chain moieties with the proper three-dimensional orientation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 22:25:25