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Titolo:
Cellular neurothekeoma of the oral mucosa
Autore:
Barrett, AW; Suhr, M;
Indirizzi:
Univ Coll London, Eastman Dent Inst Oral Healthcare Sci, Dept Oral Pathol,London WC1X 8LD, England Univ Coll London London England WC1X 8LD Pathol,London WC1X 8LD, England Univ Coll London, Eastman Dent Inst Oral Healthcare Sci, Dept Oral & Maxillofacial Surg, London WC1X 8LD, England Univ Coll London London England WC1X 8LD Surg, London WC1X 8LD, England
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 8, volume: 37, anno: 2001,
pagine: 660 - 664
SICI:
1368-8375(200112)37:8<660:CNOTOM>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
NERVE-SHEATH MYXOMA; EPITHELIOID VARIANT; BENIGN; CAVITY; SPECTRUM; TUMORS; LIGHT; FEATURES; MELANOMA; ORIGIN;
Keywords:
cellular neurothekeoma; oral mucosa;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Barrett, AW Univ Coll London, Eastman Dent Inst Oral Healthcare Sci, Dept Oral Pathol,256 Grays Inn Rd, London WC1X 8LD, England Univ Coll London 256Grays Inn Rd London England WC1X 8LD and
Citazione:
A.W. Barrett e M. Suhr, "Cellular neurothekeoma of the oral mucosa", ORAL ONCOL, 37(8), 2001, pp. 660-664

Abstract

Cellular neurothekeoma is an unusual benign neoplasm which, despite its name, is of uncertain origin. This report describes a cellular neurothekeoma of the cheek mucosa, the first at this site. The tumour presented in I 29-year-old man as I discrete mucosal thickening. Histology showed a generally well circumscribed, but unencapsulated, solid tumour which replaced the entire lamina propria and permeated between minor salivary glands and bundles of striated muscle in the submucosa. There was I sub-epithelial Grenz zone. The tumour was composed of nodules of pale, epithelioid cells separated byfascicles of spindle cells, with smaller strands and nests superficially. The nuclei were vesicular and, though mainly bland, occasionally atypical. The stroma was moderately infiltrated by mixed chronic inflammatory cells. Prominent nerves and blood vessels were seen at the periphery of the lesion, and neoplastic cells were noted within intact striated muscle fascicles. With immunohistochemistry, all the neoplastic cells strongly expressed NKI/C3, synaptophysin, neurone-specific enolase and vimentin, some expressed smooth muscle actin and PGP 9.5, but all were negative for S100, factor XIIIa, CD34, CD56, CD57, CD68, chromogranin A, desmin, epithelial membrane antigen and von Willebrand factor. The origin of the lesion is thus speculative. It was, however, completely excised Ind in 12 months there has been no recurrence. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 23:42:18