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Titolo:
Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors
Autore:
Herkel, U; Pfeiffer, N;
Indirizzi:
Univ Mainz, Augenklin, D-55101 Mainz, Germany Univ Mainz Mainz Germany D-55101 ainz, Augenklin, D-55101 Mainz, Germany
Titolo Testata:
OPHTHALMOLOGE
fascicolo: 10, volume: 98, anno: 2001,
pagine: 929 - 933
SICI:
0941-293X(200110)98:10<929:IGTGTW>2.0.ZU;2-I
Fonte:
ISI
Lingua:
GER
Soggetto:
OPEN-ANGLE GLAUCOMA; IRREVERSIBLE CORNEAL DECOMPENSATION; OCULAR HYPERTENSION; BLOOD-FLOW; INTRAOCULAR-PRESSURE; DORZOLAMIDE; LATANOPROST; BRINZOLAMIDE; TIMOLOL; COMBINATION;
Keywords:
glaucoma; topical carbonic anhydrase inhibitors dorzolamide; brinzolamide; ocular perfusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Herkel, U Univ Mainz, Augenklin, Langenbeckstr 1, D-55101 Mainz, Germany Univ Mainz Langenbeckstr 1 Mainz Germany D-55101 Mainz, Germany
Citazione:
U. Herkel e N. Pfeiffer, "Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors", OPHTHALMOLO, 98(10), 2001, pp. 929-933

Abstract

Topical carbonic anhydrase inhibitors have been used since 1995 for medical glaucoma therapy, when dorzolamide was approved. In 2000, a second carbonic anhydrase inhibitor, brinzolamide, has become available in most of Europe. Both substances exhibit a comparable intraocular pressure-lowering activitiy, however,the side-effects are somewhat different. In the five years since its introduction, dorzolamide has had a positive risk-benefit-profile. In combination with any other topical agent, carbonic anhydrase inhibitors have an additive effect on the reduction of the intraocular pressure. Animal studies suggest that dorzolamide may improve ocular blood flow indepedentof the intraocular pressure; however, the significance for human glaucoma remains to be established.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 00:40:04