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Titolo:
MRI of acute post-ischemic cerebral hemorrhage in stroke patients: diagnosis with T2*-weighted gradient-echo sequences
Autore:
Hermier, M; Nighoghossian, N; Derex, L; Bethezene, Y; Blanc-Lasserre, K; Trouillas, P; Froment, JC;
Indirizzi:
Univ Lyon 1, Hospices Civils Lyon, Hop Neurol P Wertheimer, Dept Radiol, F-69394 Lyon, France Univ Lyon 1 Lyon France F-69394 eimer, Dept Radiol, F-69394 Lyon, France CNRS, UMR 5515, CREATIS, Lyon, France CNRS Lyon FranceCNRS, UMR 5515, CREATIS, Lyon, France Univ Lyon 1, Hospices Civils Lyon, Hop Neurol P Wertheimer, Cerebrovasc Dis & Ataxia Res Ctr, F-69394 Lyon, France Univ Lyon 1 Lyon France F-69394 s & Ataxia Res Ctr, F-69394 Lyon, France Hop Neurol P Wertheimer, Serv Radiol, F-69394 Lyon, France Hop Neurol P Wertheimer Lyon France F-69394 Radiol, F-69394 Lyon, France Univ Lyon 1, Hospices Civils Lyon, Hop Croix Rousse, Dept Radiol, F-69394 Lyon, France Univ Lyon 1 Lyon France F-69394 ousse, Dept Radiol, F-69394 Lyon, France
Titolo Testata:
NEURORADIOLOGY
fascicolo: 10, volume: 43, anno: 2001,
pagine: 809 - 815
SICI:
0028-3940(200110)43:10<809:MOAPCH>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
INTRACEREBRAL HEMORRHAGE; INFARCTION; HEMATOMAS; BRAIN; SCALE;
Keywords:
stroke; brain hemorrhage; MRI; gradient-echo sequences;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Hermier, M Univ Lyon 1, Hospices Civils Lyon, Hop Neurol P Wertheimer, Dept Radiol, 59 Bd Pinel, F-69394 Lyon, France Univ Lyon 1 59 Bd Pinel Lyon France F-69394 69394 Lyon, France
Citazione:
M. Hermier et al., "MRI of acute post-ischemic cerebral hemorrhage in stroke patients: diagnosis with T2*-weighted gradient-echo sequences", NEURORADIOL, 43(10), 2001, pp. 809-815

Abstract

The use of T2*-weighted sequences has been advocated for early differentiation between hematoma and ischemia in patients with acute stroke. Early hemorrhagic transformation of ischemic stroke is an adverse event which may occur under treatment and may impair the prognosis: our aim is to evaluate the ability of T2*-weighted gradient-echo sequence (T2* GRE) to detect post-ischemic cerebral hemorrhage. The imaging procedure included: (1) baseline CT scan at admission. (2) MRI performed within 24 h of therapy onset including: (a) dual fast spin echo T2 sequence, (b) axial isotropic echoplanar diffusion-weighted imaging sequence, (c) conventional T2* GRE, and (d) 3D TOF turbo MRA. Post-ischemic cerebral hemorrhage was diagnosed if T2* GRE detected a focal intraparenchymal area of signal loss. The diameter of this lesion had to be more than 5 mm in order to eliminate past microbleeds. (3) Patients who showed an early suspicion of bleeding on MRI promptly had a second CT scan, and, if this one was negative for bleeding, another CT scan was performed 1 day later. All the other patients had a control CT scan during the first week. Forty-five consecutive patients have been included. T2* GREshowed intracranial bleeding in seven. The diagnosis of post-ischemic cerebral bleeding was confirmed by CT in all patients. Control CT scans did notreveal any post-ischemic cerebral hemorrhage in patients with negative MRI. In one case, hemorrhage was seen earlier on MRI than on CT scan. In conclusion, T2* GRE appeared to be at least as efficient as CT scan in the detection of early post-ischemic cerebral hemorrhage.

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Documento generato il 24/11/20 alle ore 13:51:38